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Articles Published Processes
9/15/2014 5:55:00 PM | Browse: 1017 | Download: 966
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Received |
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2013-06-25 09:38 |
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Peer-Review Started |
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2013-06-25 14:18 |
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To Make the First Decision |
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2013-07-26 18:33 |
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Return for Revision |
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2013-07-29 20:05 |
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Revised |
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2013-08-07 16:04 |
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Second Decision |
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2013-10-17 13:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-10-18 07:06 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-10-21 15:48 |
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Publish the Manuscript Online |
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2013-10-31 14:50 |
Category |
Neurosciences |
Manuscript Type |
Autobiography |
Article Title |
Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery
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Manuscript Source |
Invited Manuscript |
All Author List |
Vito Antonio Baldassarro, Giulia Lizzo, Michela Paradisi, Mercedes Fernández, Luciana Giardino and Laura Calzà |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Regione Emilia Romagna |
POR-FESR 2011-2014 |
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Corresponding Author |
Laura Calzà, MD, Health Science and Technologies Interdepartmental Centre for Industrial Research (HST-ICIR), University of Bologna, Via Tolara di Sopra 41/E, I-40064 Ozzano Emilia, Bologna, Italy. laura.calza@unibo.it |
Key Words |
Neural stem cells; Alzheimer’s disease; Neuron maturation; Drug discovery |
Core Tip |
In this study neural stem cells isolated from Tg2576 mice are characterized as an in vitro model for Alzheimer’s disease. These cells represent a robust system for studying pathological mechanisms related to Aβ intracellular accumulation, such as stem cell status, or during differentiation processes. This model could provide a new cell platform for developing and screening new molecules. |
Publish Date |
2013-10-31 14:50 |
Citation |
Baldassarro VA, Lizzo G, Paradisi M, Fernández M, Giardino L, Calzà L. Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery. World J Stem Cells 2013; 5(4): 229-237 |
URL |
http://www.wjgnet.com/1948-0210/full/v5/i4/229.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v5.i4.229 |
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