Publication Name	World Journal of Gastroenterology
Manuscript ID	4305
Country	United States

Received	2013-06-26 10:28
Peer-Review Started	2013-06-26 16:08
To Make the First Decision	2013-08-08 11:13
Return for Revision	2013-08-08 17:52
Revised
Second Decision	2013-09-16 17:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-09-17 06:39
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-04 09:44
Publish the Manuscript Online	2013-11-18 10:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula
Manuscript Source	Invited Manuscript
All Author List	Hari Sayana, Osama Yousef and Wendell K Clarkston
Funding Agency and Grant Number
Corresponding Author	Hari Sayana, MD, Section of Gastroenterology and Hepatology, Department of Internal Medicine, University of Missouri Kansas City, 2301 Holmes Street, Kansas City, MO 64108-2640, United States. sayana_h@yahoo.com
Key Words	Hepatocellular carcinoma; Hepatogastric fistula; Fistula; Upper gastrointestinal bleeding
Core Tip	Gastrointestinal bleeding is a common complication of hepatocellular carcinoma (HCC). However, HCC leading to Hepatogastric fistula presenting as massive upper gastrointestinal bleeding is uncommon. Here we report a case of HCC with direct invasion of the stomach leading to massive gastrointestinal bleeding. Patient was managed with selective arterial angiogram and coil embolization to control bleeding. HCC with local metastasis to adjacent structures such gastrointestinal tract carries poor prognosis. With increasing incidence of HCC and recent improvements in the treatment of advanced HCC, this condition may become more common and awareness among clinicians should help consider this condition in the differential diagnosis and prompt management.
Publish Date	2013-11-18 10:59
Citation	Sayana H, Yousef O, Clarkston WK. Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula. World J Gastroenterol 2013; 19(42): 7472-7475
URL	http://www.wjgnet.com/1007-9327/full/v19/i42/7472.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i42.7472

Full Article (PDF)	WJG-19-7472.pdf
Manuscript File	4305-Review.docx
Answering Reviewers	4305-Answering reviewers.pdf
Copyright License Agreement	4305-Copyright assignment.pdf
Peer-review Report	4305-Peer review.pdf
Scientific Editor Work List	4305-Scientific editor work list.doc