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Articles Published Processes
12/27/2018 8:56:32 AM | Browse: 754 | Download: 1479
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Received |
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2018-11-09 02:06 |
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Peer-Review Started |
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2018-11-12 02:29 |
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To Make the First Decision |
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2018-11-29 09:23 |
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Return for Revision |
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2018-12-07 01:32 |
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Revised |
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2018-12-08 02:31 |
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Second Decision |
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2018-12-13 09:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-12-13 17:34 |
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Articles in Press |
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2018-12-13 17:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-12-17 23:20 |
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Typeset the Manuscript |
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2018-12-26 03:09 |
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Publish the Manuscript Online |
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2018-12-27 08:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Safety of hepatitis B virus core antigen-positive grafts in liver transplantation: A single-center experience in China
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming Lei, Lu-Nan Yan, Jia-Yin Yang, Tian-Fu Wen, Bo Li, Wen-Tao Wang, Hong Wu, Ming-Qing Xu, Zhe-Yu Chen and Yong-Gang Wei |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lu-Nan Yan, MD, Professor, Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China. yanlunan688@126.com |
| Key Words |
Liver transplantation; Long-term outcome; Hepatitis B core antibody; Hepatitis B virus infection |
| Core Tip |
Considering the shortage of suitable liver grafts for liver transplantation, using hepatitis B virus core antibody positive (HBcAb+) livers might be a possible way to enlarge the donor pool. However, the safety is controversial and not widely evaluated in Chinese patients. Our retrospective study enrolling 1071 patients found that HBcAb+ grafts did not affect the long-term outcome. Although post-transplant hepatitis B virus (HBV) infection had a relatively higher incidence in HBV surface antigen-negative patients with such grafts, it did not affect patient and graft survival. We also found that sufficient anti-HBs titers in recipients might be a protective factor against de novo HBV infection. Combined with proper postoperative antiviral prophylaxis, utilization of HBcAb+ grafts is feasible. |
| Publish Date |
2018-12-27 08:56 |
| Citation |
Lei M, Yan LN, Yang JY, Wen TF, Li B, Wang WT, Wu H, Xu MQ, Chen ZY, Wei YG. Safety of hepatitis B virus core antigen-positive grafts in liver transplantation: A single-center experience in China. World J Gastroenterol 2018; 24(48): 5525-5536 |
| URL |
https://www.wjgnet.com/1007-9327/full/v24/i48/5525.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v24.i48.5525 |
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