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Articles Published Processes
2/15/2019 9:46:41 AM | Browse: 1170 | Download: 1785
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Received |
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2018-11-06 07:14 |
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Peer-Review Started |
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2018-11-10 08:33 |
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First Decision by Editorial Office Director |
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2018-11-28 06:58 |
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Return for Revision |
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2018-12-05 06:24 |
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Revised |
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2018-12-11 16:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-12-29 02:17 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2019-01-01 15:32 |
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Articles in Press |
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2019-01-01 15:32 |
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Edit the Manuscript by Language Editor |
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2019-01-11 18:54 |
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Typeset the Manuscript |
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2019-02-15 01:28 |
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Publish the Manuscript Online |
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2019-02-15 09:46 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
AU-rich elements-binding proteins in colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Noémie Legrand, Dan A Dixon and Cyril Sobolewski |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ligue Genevoise Contre le Cancer (Cyril Sobolewski) |
1711 |
| National Institutes of Health/National Cancer Institute Cancer Center (Dan A. Dixon) |
P30 CA168524 |
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| Corresponding Author |
Cyril Sobolewski, PhD, Research Associate, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CMU, 1 rue Michel-Servet, Geneva CH-1211, Switzerland. cyril.sobolewski@unige.ch |
| Key Words |
Colorectal cancer; Adenylate-Uridylate-rich elements binding proteins; Oncogenes; Tumor suppressors; Post-transcriptional regulation |
| Core Tip |
Colorectal cancer (CRC) is a deadly cancer associated with the deregulation of multiple genetic and epigenetic mechanisms leading to the silencing of tumor suppressors as well as the induction of oncogenes and inflammatory-related genes. Among them, a novel class of RNA-binding proteins called Adenylate-Uridylate-rich elements binding proteins have been involved in the post-transcriptional regulation of genes linked to CRC tumorigenesis. Current findings indicate the major regulatory roles these RNA-binding proteins on deregulated pathways associated with CRC. Therefore, targeting these proteins may represent a novel and efficient therapeutic approach. |
| Publish Date |
2019-02-15 09:46 |
| Citation |
Legrand N, Dixon DA, Sobolewski C. AU-rich elements-binding proteins in colorectal cancer. World J Gastrointest Oncol 2019; 11(2): 71-90 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i2/71.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i2.71 |
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