| ISSN |
1948-5204 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Glycerophospholipids pathways and chromosomal instability in gastric cancer: Global lipidomics analysis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Cheng-Yu Hung, Ta-Sen Yeh, Cheng-Kun Tsai, Ren-Chin Wu, Ying-Chieh Lai, Meng-Han Chiang, Kuan-Ying Lu, Chia-Ni Lin, Mei-Ling Cheng and Gigin Lin |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the funding from the Ministry of Science and Technology Taiwan grant |
MOST 106-2314-B-182A-019-MY3 |
| the Chang Gung Foundation |
CMRPG3E1321-2 |
|
| Corresponding Author |
Gigin Lin, MD, PhD, Director, Doctor, Medical Imaging and Intervention, Imaging Core Lab, Institute for Radiological Research, Metabolomics Core Lab, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Fuhsing 5, Guishan 333, Taoyuan, Taiwan. giginlin@cgmh.org.tw |
| Key Words |
Chromosomal instability; Gastric cancer; Glycerophospholipids; Metabolomics; Lipidomics profile |
| Core Tip |
We investigated the correlation between comprehensive lipidomic profiles of gastric cancer and the tumor’s chromosomal instability (CIN) status. In this disease landscape study, which involved no pre-specified hypotheses, we combined a gene molecule classification method with a lipidomic method to discover metabolic information for accurate tumor classification. CIN-status-based lipidomics profiling demonstrated translational potential for biomarker discovery and development of novel therapeutic strategies. |
| Publish Date |
2019-03-15 06:26 |
| Citation |
Hung CY, Yeh TS, Tsai CK, Wu RC, Lai YC, Chiang MH, Lu KY, Lin CN, Cheng ML, Lin G. Glycerophospholipids pathways and chromosomal instability in gastric cancer: Global lipidomics analysis. World Journal of Gastrointestinal Oncology 2019; 11(3): 181-194 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i3/181.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i3.181 |
