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Articles Published Processes
3/26/2019 7:46:36 AM | Browse: 982 | Download: 1800
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Received |
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2018-11-10 08:46 |
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Peer-Review Started |
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2018-11-11 12:11 |
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To Make the First Decision |
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2018-11-29 07:59 |
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Return for Revision |
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2018-12-05 08:00 |
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Revised |
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2019-01-28 13:45 |
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Second Decision |
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2019-03-07 09:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-12 22:49 |
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Articles in Press |
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2019-03-12 22:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-03-26 04:06 |
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Publish the Manuscript Online |
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2019-03-26 07:46 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Basic Study |
Article Title |
Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Nicola Alessio, Tiziana Squillaro, Vincenzo Monda, Gianfranco Peluso, Marcellino Monda, Mariarosa AB Melone, Umberto Galderisi and Giovanni Di Bernardo |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
2018 Grant of Experimental Medicine Department (Luigi Vanvitelli Campania University) to Umberto Galderisi and Marcellino Monda (partially) |
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Corresponding Author |
Giovanni Di Bernardo, PhD, Associate Professor, Department of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania Luigi Vanvitelli, Via S.M. Costantinopoli 16, Naples 80138, Italy. gianni.dibernardo@unicampania.it |
Key Words |
Mesenchymal stromal cells; Senescence; Cytokines; Adipogenesis; Brown fat |
Core Tip |
Obesity may receive new hints from studies on skinny people (SP). These are individuals who show a poor or null gaining of body weight, in spite of high-calorie intake, by far exceeding the body requirements. We evaluated how circulating factors present in the SP sera may affect adipogenesis of mesenchymal stromal cells. Our finding suggests that sera from SP may promote brown adipogenesis rather that white adipocyte differentiation. Our data could explain why SP present normal body composition in spite of an excess of caloric intake. |
Publish Date |
2019-03-26 07:46 |
Citation |
Alessio N, Squillaro T, Monda V, Peluso G, Monda M, Melone MA, Galderisi U, Di Bernardo G. Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells. World J Stem Cells 2019; 11(3): 180-195 |
URL |
https://www.wjgnet.com/1948-0210/full/v11/i3/180.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v11.i3.180 |
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