Publication Name	World Journal of Gastroenterology
Manuscript ID	4354
Country	Japan

Received	2013-06-28 09:46
Peer-Review Started	2013-06-28 15:45
To Make the First Decision	2013-07-19 08:38
Return for Revision	2013-07-20 13:23
Revised	2013-07-31 18:34
Second Decision	2013-08-16 19:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-16 23:29
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-21 12:08
Publish the Manuscript Online	2013-11-13 08:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Case Report
Article Title	Adjuvant surgery for advanced extrahepatic cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Yukio Oshiro, Kazuhiro Takahashi, Ryoko Sasaki, Tadashi Kondo, Shingo Sakashita and Nobuhiro Ohkohchi
Funding Agency and Grant Number
Corresponding Author	Yukio Oshiro, MD, PhD, Department of Surgery, Division of Gastroenterological and Hepatobiliary Surgery, and Organ Transplantation, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan. oshiro@md.tsukuba.ac.jp
Key Words	Extrahepatic cholangiocarcinoma; Adjuvant surgery; Conversion surgery; Chemotherapy; Gemcitabine
Core Tip	Patients with Stage Ⅳ cholangiocarcinoma are currently not considered to be surgical candidates and are typically offered systemic chemotherapy. Recently, several novel systemic chemotherapy regimens have allowed an initially unresectable cholangiocarcinoma to be resectable. In a patient with advanced extrahepatic cholangiocarcinoma, gemcitabine (GEM) induced a dramatic reduction of the tumor, which led to curative resection and a long-term survival of 6 years and 9 mo. This result suggests the possibility of advantages of using GEM for the treatment of advanced cholangiocarcinoma, and GEM-based chemotherapy could be performed more often for unresectable cholangiocarcinomas.
Publish Date	2013-11-13 08:37
Citation	Oshiro Y, Takahashi K, Sasaki R, Kondo T, Sakashita S, Ohkohchi N. Adjuvant surgery for advanced extrahepatic cholangiocarcinoma. World J Gastroenterol 2013; 19(40): 6934-6938
URL	http://www.wjgnet.com/1007-9327/full/v19/i40/6934.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i40.6934

Full Article (PDF)	WJG-19-6934.pdf
Manuscript File	4354-Review.docx
Answering Reviewers	4354-Answering reviewers.pdf
Copyright License Agreement	4354-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4354-Language certificate.pdf
Peer-review Report	4354-Peer review(s).pdf
Scientific Editor Work List	4354-Scientific editor work list.doc