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Articles Published Processes
9/15/2014 11:27:00 AM | Browse: 1096 | Download: 1126
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Received |
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2013-06-28 10:51 |
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Peer-Review Started |
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2013-06-28 16:50 |
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To Make the First Decision |
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2013-08-08 11:11 |
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Return for Revision |
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2013-08-19 20:14 |
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Revised |
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2013-08-21 22:14 |
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Second Decision |
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2013-10-16 11:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-10-16 12:08 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-10-25 15:59 |
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Publish the Manuscript Online |
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2013-12-18 16:32 |
Category |
Pharmacology & Pharmacy |
Manuscript Type |
Minireviews |
Article Title |
Statins role in cancer prevention and development-recent meta-analyses
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Manuscript Source |
Invited Manuscript |
All Author List |
Martin Künzl, Christine Wasinger and Martin Hohenegger |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Herzfeldersche Familienstiftung and the Austrian Science foundation |
P22385 |
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Corresponding Author |
Martin Hohenegger, MD, Associate Professor, Medical University of Vienna, Center for Physiology and Pharmacology, Institute of Pharmacology, Währingerstrasse 13A, A-1090 Vienna, Austria. martin.hohenegger@meduniwien.ac.at |
Key Words |
3-Hydroxy-3-methylglutaryl-coenzyme A-reductase inhibitors; Low density lipoprotein cholesterol; Cancer; Breast cancer; Apoptosis; Statins |
Core Tip |
The 3-hydroxy-3 methyl CoA (HMG-CoA) reductase inhibitors, the statins are one of the most frequently prescribed drugs in industrialized countries. Statins are well tolerated cholesterol lowering drugs which significantly help to reduce cardiovascular events. Clinical trials and meta-analyzes thereof now accumulate evidence that development of cancer might be reduced in some tissues. In this review the current status of evidence for an anti-cancer effect of statins will be critically evaluated. In particular, colon and prostate cancer are assessed in greater detail. |
Publish Date |
2013-12-18 16:32 |
Citation |
Künzl M, Wasinger C, Hohenegger M. Statins role in cancer prevention and development-recent meta-analyses. World J Pharmacol 2013; 2(4): 100-106 |
URL |
http://www.wjgnet.com/2220-3192/full/v2/i4/100.htm |
DOI |
http://dx.doi.org/10.5497/wjp.v2.i4.100 |
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