Publication Name	World Journal of Orthopedics
Manuscript ID	4369
Country	Greece

Received	2013-06-28 11:32
Peer-Review Started	2013-06-28 17:40
To Make the First Decision	2013-07-19 08:37
Return for Revision	2013-07-19 22:07
Revised	2013-09-17 22:53
Second Decision	2013-11-01 16:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-03 11:08
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-14 15:48
Publish the Manuscript Online	2014-01-20 10:25

ISSN	2218-5836 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Use of demineralized bone matrix in spinal fusion
Manuscript Source	Invited Manuscript
All Author List	Konstantinos Tilkeridis, Panagiotis Touzopoulos, Athanasios Ververidis, Sotirios Christodoulou, Konstantinos Kazakos and Georgios I Drosos
Funding Agency and Grant Number
Corresponding Author	Georgios I Drosos, MD, PhD, Assistant Professor of Orthopaedics, Department of Orthopaedic Surgery, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, Farm Nea Makri, 68100 Alexandroupolis, Greece. drosos@otenet.gr
Key Words	Bone grafts; Demineralized bone matrix; Spinal fusion; Scoliosis
Core Tip	It is widely accepted that autologous iliac crest bone graft (ICBG) is considered the gold-standard for spinal fusion surgery, although it is associated with a series of complications and a morbidity rate. Demineralized bone matrix (DBM) could be successfully used as a potential graft extender, enhancer or substitute. Spinal surgeons can take advance of DBMs osteoinductivity and osteoconductivity and achieve good results in spinal fusion, with a significantly lower complication rate and results similar to these of ICBG. The most significant drawbacks to DBM may be the difference between and within products so, it is important the surgeon to remain updated of the product properties to optimize the successful use of DBM, and the fact that it is not useful as a structural graft material because of its amorphous consistency, so it has to be used in combination with other type of grafts or scaffolds increasing the cost.
Publish Date	2014-01-20 10:25
Citation	Tilkeridis K, Touzopoulos P, Ververidis A, Christodoulou S, Kazakos K, Drosos GI. Use of demineralized bone matrix in spinal fusion. World J Orthop 2014; 5(1): 30-37
URL	http://www.wjgnet.com/2218-5836/full/v5/i1/30.htm
DOI	http://dx.doi.org/10.5312/wjo.v5.i1.30

Full Article (PDF)	WJO-5-30.pdf
Full Article (Word)	WJO-5-30.doc
Manuscript File	4369-Review.doc
Answering Reviewers	4369-Answering reviewers.pdf
Copyright License Agreement	4369-Copyright assignment.pdf
Peer-review Report	4369-Peer review(s).pdf
Scientific Editor Work List	4369-Scientific editor work list.doc