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Articles Published Processes
9/15/2014 11:48:00 AM | Browse: 1051 | Download: 1478
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Received |
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2013-06-28 11:48 |
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Peer-Review Started |
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2013-06-28 17:52 |
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To Make the First Decision |
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2013-07-19 08:37 |
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Return for Revision |
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2013-07-19 21:57 |
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Revised |
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2013-08-10 16:37 |
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Second Decision |
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2013-11-01 16:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-11-03 11:09 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-11-19 14:14 |
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Publish the Manuscript Online |
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2014-01-11 22:13 |
Category |
Psychiatry |
Manuscript Type |
Review |
Article Title |
Brain-derived neurotrophic factor as a potential biomarker of cognitive recovery in schizophrenia
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Manuscript Source |
Invited Manuscript |
All Author List |
Rafael Penadés, Rosa Catalán, Irene López-Vílchez, Bárbara Arias, Alexandre González-Rodríguez, Ana M Galán and Cristóbal Gastó |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Instituto de Salud Carlos III of FIS |
PI 11/01958 |
CIBERSAM |
to Penadés R |
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Corresponding Author |
Dr. Rafael Penadés, PhD, Psychiatry and Psychology, Clinical Institute of Neurosciences (ICN), Hospital Clínic, C/ Villarroel 170, 08036 Barcelona, Spain. rpenades@clinic.ub.es |
Key Words |
Schizophrenia; Brain-derived neurotrophic factor; Cognition; Biomarkers |
Core Tip |
The lack of diagnostic and treatment markers is one of the most important problems in clinical practice. Brain-derived neurotrophic factor (BDNF) has been proposed as a biomarker of schizophrenia and, more specifically, as a biomarker of cognitive recovery. Evidence collected in this review indicates that there is evidence suggesting that serum BDNF levels are involved in some synaptic plasticity processes. Additionally, serum BDNF levels significantly increased in schizophrenia subjects after neuroplasticity-based cognitive training. All in all, the current consideration of BDNF as a biomarker of cognitive recovery in schizophrenia is promising but still premature. |
Publish Date |
2014-01-11 22:13 |
Citation |
Penadés R, Catalán R, López-Vílchez I, Arias B, González-Rodríguez A, Galán AM, Gastó C. Brain-derived neurotrophic factor as a potential biomarker of cognitive recovery in schizophrenia. World J Psychiatr 2013; 3(4): 93-102 |
URL |
http://www.wjgnet.com/2220-3206/full/v3/i4/93.htm |
DOI |
http://dx.doi.org/10.5498/wjp.v3.i4.93 |
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