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Articles Published Processes
9/20/2014 7:36:00 PM | Browse: 1121 | Download: 954
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Received |
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2013-06-28 12:30 |
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Peer-Review Started |
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2013-06-28 19:05 |
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To Make the First Decision |
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2013-07-05 18:33 |
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Return for Revision |
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2013-07-09 12:53 |
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Revised |
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2013-07-31 19:31 |
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Second Decision |
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2013-08-16 19:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-08-17 00:12 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-09-23 17:10 |
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Publish the Manuscript Online |
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2013-09-26 18:43 |
Category |
Neurosciences |
Manuscript Type |
Minireviews |
Article Title |
Variation in experimental autoimmune encephalomyelitis scores in a mouse model of multiple sclerosis
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Manuscript Source |
Invited Manuscript |
All Author List |
Chisen Takeuchi, Kanato Yamagata and Takako Takemiya |
Funding Agency and Grant Number |
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Corresponding Author |
Takako Takemiya, Associate Professor, Medical Research Institute, Tokyo Women’s Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666, Japan. takakot@lab.twmu.ac.jp
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Key Words |
Multiple sclerosis; Experimental autoimmune encephalomyelitis; Experimental autoimmune encephalomyelitis score; Motor dysfunction |
Core Tip |
Multiple sclerosis (MS) is a common demyelinating central nervous system disease associated with progressive physical impairment. Experimental autoimmune encephalomyelitis (EAE) is often used as an animal model to study MS. EAE can be induced in various species by introducing specific antigens, and the severity of the paralysis is indicated using the EAE score. The score is simple and easy to use, however, its application varies between laboratories, and the scoring is dependent on the subjective bias of the researchers. We described the criteria used for the EAE scoring systems in various laboratories, to facilitate the study of MS.
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Publish Date |
2013-09-26 18:43 |
Citation |
Takeuchi C, Yamagata K, Takemiya T. Variation in experimental autoimmune encephalomyelitis scores in a mouse model of multiple sclerosis. World J Neurol 2013; 3(3): 56-61 |
URL |
http://www.wjgnet.com/2218-6212/full/v3/i3/56.htm |
DOI |
http://dx.doi.org/10.5316/wjn.v3.i3.56 |
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