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Articles Published Processes
9/11/2014 8:39:00 PM | Browse: 690 | Download: 730
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Received |
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2013-06-29 09:48 |
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Peer-Review Started |
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2013-07-01 13:55 |
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To Make the First Decision |
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2013-07-26 18:29 |
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Return for Revision |
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2013-07-31 16:48 |
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Revised |
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2013-09-01 11:26 |
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Second Decision |
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2013-09-29 10:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-09-29 22:07 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-11-24 15:39 |
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Typeset the Manuscript |
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2013-12-02 15:04 |
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Publish the Manuscript Online |
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2013-12-18 10:00 |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Autobiography |
Article Title |
Silencing Bmi-1 enhances the senescence and decreases the metastasis of human gastric cancer cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Feng-Lan Gao, Wei-Shan Li, Chun-Ling Liu and Guo-Qiang Zhao |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Provincial Nature Science Foundation of Henan Education Department |
2009C310007 (to Gao FL) |
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Corresponding Author |
Feng-Lan Gao, Professor, Pathological Examination and Research Center, Luohe Medical College, College Road, Huiyuan District, Luohe 462002, Henan Province, China. lmcgfl@163.com |
Key Words |
Bmi-1; Gastric cancer; Senescence; Metastasis |
Core Tip |
The overexpression of Bmi-1 contributes to the development of cancers. This study aimed at to evaluate the impact of Bmi-1 on the senescence and metastasis of human gastric cancer. The results demonstrated that inhibition of Bmi-1 gene expression can enhance the senescence of human gastric cancer cells and inhibit the invasion and metastasis of gastric cancer. This research has provided an indication that Bmi-1 inhibitors might be developed as new agents for gastric cancer. |
Publish Date |
2013-12-18 10:00 |
Citation |
Gao FL, Li WS, Liu CL, Zhao GQ. Silencing Bmi-1 enhances the senescence and decreases the metastasis of human gastric cancer cells. World J Gastroenterol 2013; 19(46): 8764-8769 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i46/8764.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i46.8764 |
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