Publication Name	World Journal of Gastroenterology
Manuscript ID	4411
Country	China

Received	2013-06-29 09:48
Peer-Review Started	2013-07-01 13:55
First Decision by Editorial Office Director
Return for Revision	2013-07-31 16:48
Revised	2013-09-01 11:26
Publication Fee Transferred
Second Decision by Editor	2013-09-29 10:13
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-09-29 22:07
Articles in Press
Edit the Manuscript by Language Editor	2013-11-24 15:39
Typeset the Manuscript	2013-12-02 15:04
Publish the Manuscript Online	2013-12-18 10:00

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Autobiography
Article Title	Silencing Bmi-1 enhances the senescence and decreases the metastasis of human gastric cancer cells
Manuscript Source	Invited Manuscript
All Author List	Feng-Lan Gao, Wei-Shan Li, Chun-Ling Liu and Guo-Qiang Zhao
Funding Agency and Grant Number	Funding Agency Grant Number Provincial Nature Science Foundation of Henan Education Department 2009C310007 (to Gao FL)
Corresponding Author	Feng-Lan Gao, Professor, Pathological Examination and Research Center, Luohe Medical College, College Road, Huiyuan District, Luohe 462002, Henan Province, China. lmcgfl@163.com
Key Words	Bmi-1; Gastric cancer; Senescence; Metastasis
Core Tip	The overexpression of Bmi-1 contributes to the development of cancers. This study aimed at to evaluate the impact of Bmi-1 on the senescence and metastasis of human gastric cancer. The results demonstrated that inhibition of Bmi-1 gene expression can enhance the senescence of human gastric cancer cells and inhibit the invasion and metastasis of gastric cancer. This research has provided an indication that Bmi-1 inhibitors might be developed as new agents for gastric cancer.
Publish Date	2013-12-18 10:00
Citation	Gao FL, Li WS, Liu CL, Zhao GQ. Silencing Bmi-1 enhances the senescence and decreases the metastasis of human gastric cancer cells. World J Gastroenterol 2013; 19(46): 8764-8769
URL	http://www.wjgnet.com/1007-9327/full/v19/i46/8764.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i46.8764

Full Article (PDF)	WJG-19-8764.pdf
Manuscript File	4411-Review.doc
Answering Reviewers	4411-Answering reviewers.pdf
Copyright License Agreement	4411-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4411-Language certificate.pdf
Peer-review Report	4411-Peer reviewer(s).pdf
Scientific Editor Work List	4411-Scientific editor work list.doc