Publication Name	World Journal of Gastroenterology
Manuscript ID	4436
Country	China

Received	2013-06-29 19:43
Peer-Review Started	2013-06-29 21:12
To Make the First Decision	2013-08-21 18:34
Return for Revision	2013-08-22 19:03
Revised	2013-09-10 01:16
Second Decision	2013-09-29 11:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-29 21:59
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-10-15 14:18
Typeset the Manuscript	2013-11-04 10:38
Publish the Manuscript Online	2013-11-18 10:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Radiofrequency ablation of hepatocellular carcinoma sized > 3 and ≤ 5 cm: Is ablative margin of more than 1 cm justified?
Manuscript Source	Invited Manuscript
All Author List	Shan Ke, Xue-Mei Ding, Xiao-Jun Qian, Yi-Ming Zhou, Bao-Xin Cao, Kun Gao and Wen Bing Sun
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30872490 National Natural Science Foundation of China 81172320 Dr. Wu Jie-Ping Medical Foundation 320675012712 Dr. Wu Jie-Ping Medical Foundation 320675007131
Corresponding Author	Wen-Bing Sun, MD, PhD, Department of Hepatobiliary Surgery, Chao-yang Hospital Affiliated to Capital Medical University, Beijing Gongren Tiyuchang Nan Road No. 8, Beijing 100043, China. cyhswb@qq.com
Key Words	Hepatocellular carcinoma; Radiofrequency ablation; Ablative margin; Recurrence; Survival
Core Tip	Recurrence is the most important factor for prognosis of hepatocellular carcinoma (HCC) after radiofrequency ablation. Although a sufficient ablative margin (AM) is an essential way to minimize recurrence risk, the optimal AM for HCC tumors 3.1 to 5.0 cm remains controversial. This study provides evidence that, for HCC tumors 3.1 to 5.0 cm, AMs > 1.0 cm could reduce chance of recurrence compared to AMs of 0.5-1.0 cm, which emphasizes the need for more strategic AMs that are > 1.0 cm for ablation of HCC tumors of 3.1 to 5.0 cm.
Publish Date	2013-11-18 10:59
Citation	Ke S, Ding XM, Qian XJ, Zhou YM, Cao BX, Gao K, Sun WB. Radiofrequency ablation of hepatocellular carcinoma sized > 3 and ≤ 5 cm: Is ablative margin of more than 1 cm justified? World J Gastroenterol 2013; 19(42): 7389-7398
URL	http://www.wjgnet.com/1007-9327/full/v19/i42/7389.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i42.7389

Full Article (PDF)	WJG-19-7389.pdf
Manuscript File	4436-Review.doc
Answering Reviewers	4436-Answering reviewers.pdf
Copyright License Agreement	4436-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4436-Language certificate.pdf
Peer-review Report	4436-Peer review(s).pdf
Scientific Editor Work List	4436-Scientific editor work list.doc