BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/6/2019 2:06:54 AM | Browse: 1051 | Download: 1375
Publication Name World Journal of Gastroenterology
Manuscript ID 44654
Country/Territory Germany
Received
2018-11-25 07:20
Peer-Review Started
2018-11-26 02:45
To Make the First Decision
2018-12-29 00:52
Return for Revision
2018-12-29 05:37
Revised
2019-03-27 02:18
Second Decision
2019-03-29 10:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-30 00:47
Articles in Press
2019-03-30 00:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-04-30 00:24
Publish the Manuscript Online
2019-05-06 02:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Efficacy of Detoxsan® powder on diarrhea caused by gastrointestinal neuroendocrine tumors
Manuscript Source Unsolicited Manuscript
All Author List Thomas Langbein, Wilfried Dathe, Anika Deuerling and Richard P. Baum
ORCID
Author(s) ORCID Number
Thomas Langbein http://orcid.org/0000-0003-4258-5687
Wilfried Dathe http://orcid.org/0000-0002-6894-4898
Anika Deuerling http://orcid.org/0000-0001-8337-7484
Richard P. Baum http://orcid.org/0000-0003-1723-0075
Funding Agency and Grant Number
Corresponding Author Wilfried Dathe, DSc, PhD, Doctor, Scientific Managment, Heck Bio-Pharma GmbH, Gerberstraße 15, Winterbach D-73650, Germany. wilfried.dathe@gmx.de
Key Words Neuroendocrine tumor; Diarrhea; Carcinoid syndrome; Treatment; Clinoptilolite; Mordenite; Zeolite
Core Tip A well characterized zeolite (Detoxsan® powder) was applied to patients with neuroendocrine tumors (NETs) of the gastrointestinal tract suffer suffered from therapy-refractory diarrhea either by its frequency or by watery stool, despite receiving standard pharmacotherapy according to the guidelines for carcinoid syndrome and comorbidities. In 15 of 20 patients (approximately 75%) bowel movement rate could be normalized. Thus, Detoxsan® powder acts as an adsorbent and is able to reduce significantly symptoms of diarrhea in patients suffering from NETs. However, dose and period of intake have to be individually adjusted.
Publish Date 2019-05-06 02:06
Citation Langbein T, Dathe W, Deuerling A, Baum RP. Efficacy of Detoxsan® powder on diarrhea caused by gastrointestinal neuroendocrine tumors. World J Gastroenterol 2019; 25(17): 2133-2143
URL https://www.wjgnet.com/1007-9327/full/v25/i17/2133.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i17.2133
Full Article (PDF) WJG-25-2133.pdf
Full Article (Word) WJG-25-2133.docx
Manuscript File 44654-Review.docx
Answering Reviewers 44654-Answering reviewers.pdf
Audio Core Tip 44654-Audio core tip.mp3
Biostatistics Review Certificate 44654-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 44654-Conflict-of-interest statement.pdf
Copyright License Agreement 44654-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 44654-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 44654-Institutional review board statement.pdf
Peer-review Report 44654-Peer-review(s).pdf
Scientific Misconduct Check 44654-Scientific misconduct check.pdf
Scientific Editor Work List 44654-Scientific editor work list.pdf