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Articles Published Processes
5/6/2019 2:06:54 AM | Browse: 1196 | Download: 1849
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Received |
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2018-11-25 07:20 |
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Peer-Review Started |
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2018-11-26 02:45 |
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To Make the First Decision |
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2018-12-29 00:52 |
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Return for Revision |
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2018-12-29 05:37 |
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Revised |
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2019-03-27 02:18 |
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Second Decision |
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2019-03-29 10:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-30 00:47 |
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Articles in Press |
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2019-03-30 00:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-04-30 00:24 |
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Publish the Manuscript Online |
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2019-05-06 02:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Efficacy of Detoxsan® powder on diarrhea caused by gastrointestinal neuroendocrine tumors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Thomas Langbein, Wilfried Dathe, Anika Deuerling and Richard P. Baum |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wilfried Dathe, DSc, PhD, Doctor, Doctor, Scientific Managment, Heck Bio-Pharma GmbH, Gerberstraße 15, Winterbach D-73650, Germany. wilfried.dathe@gmx.de |
| Key Words |
Neuroendocrine tumor; Diarrhea; Carcinoid syndrome; Treatment; Clinoptilolite; Mordenite; Zeolite |
| Core Tip |
A well characterized zeolite (Detoxsan® powder) was applied to patients with neuroendocrine tumors (NETs) of the gastrointestinal tract suffer suffered from therapy-refractory diarrhea either by its frequency or by watery stool, despite receiving standard pharmacotherapy according to the guidelines for carcinoid syndrome and comorbidities. In 15 of 20 patients (approximately 75%) bowel movement rate could be normalized. Thus, Detoxsan® powder acts as an adsorbent and is able to reduce significantly symptoms of diarrhea in patients suffering from NETs. However, dose and period of intake have to be individually adjusted. |
| Publish Date |
2019-05-06 02:06 |
| Citation |
Langbein T, Dathe W, Deuerling A, Baum RP. Efficacy of Detoxsan® powder on diarrhea caused by gastrointestinal neuroendocrine tumors. World J Gastroenterol 2019; 25(17): 2133-2143 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i17/2133.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i17.2133 |
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