Publication Name	World Journal of Gastroenterology
Manuscript ID	4470
Country	Taiwan

Received	2013-07-01 11:31
Peer-Review Started	2013-07-02 09:47
To Make the First Decision	2013-07-26 18:35
Return for Revision	2013-07-29 14:27
Revised	2013-08-15 22:52
Second Decision	2013-08-29 07:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-29 10:02
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-29 12:22
Publish the Manuscript Online	2013-12-18 10:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Application of quantitative estimates of fecal hemoglobin concentration for risk prediction of colorectal neoplasia
Manuscript Source	Invited Manuscript
All Author List	Chao-Sheng Liao, Yu-Min Lin, Hung-Chuen Chang, Yu-Hung Chen, Lee-Won Chong, Chun-Hao Chen, Yueh-Shih Lin, Kuo-Ching Yang and Chia-Hui Shih
Funding Agency and Grant Number
Corresponding Author	Yu-Min Lin, MD, Division of Gastroenterology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, No. 95, Wen Chang Road, Shih Lin District, Taipei 111, Taiwan. M001063@ms.skh.org.tw
Key Words	Colorectal cancer; Fecal immunochemical test; Screening; Risk prediction; Performance
Core Tip	The fecal immunochemical test (FIT) for hemoglobin is specific for detecting colorectal lesions. With adjustment for age and gender of 17 881 attendees at a colorectal cancer screening program in a single hospital, we demonstrated that higher FIT concentrations were associated with more advanced histological grades (β= 0.088, P < 0.01). A significant log-linear relationship was found between the FIT concentration and positive predictive value of the FIT for predicting colorectal tumors (R2 > 0.95, P < 0.001). Risk stratification for colorectal neoplasia based on individual FIT concentration may help to improve the performance of screening programs.
Publish Date	2013-12-18 10:39
Citation	Liao CS, Lin YM, Chang HC, Chen YH, Chong LW, Chen CH, Lin YS, Yang KC, Shih CH. Application of quantitative estimates of fecal hemoglobin concentration for risk prediction of colorectal neoplasia. World J Gastroenterol 2013; 19(45): 8366-8372
URL	http://www.wjgnet.com/1007-9327/full/v19/i45/8366.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i45.8366

Full Article (PDF)	WJG-19-8366.pdf
Manuscript File	4470-Review.doc
Answering Reviewers	4470-Answering reviewers.pdf
Copyright License Agreement	4470-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4470-Language certificate.pdf
Peer-review Report	4470-Peer review(s).pdf
Scientific Editor Work List	4470-Scientific editor work list.doc