| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Plasma microRNAs as potential new biomarkers for early detection of early gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Liang Zhu, Long-Fei Ren, Hai-Ping Wang, Zhong-Tian Bai, Lei Zhang, Wen-Bo Meng, Ke-Xiang Zhu, Fang-Hui Ding, Long Miao, Jun Yan, Yan-Ping Wang, Yu-Qin Liu, Wen-Ce Zhou and Xun Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Health Industry Research Project of Gansu province |
GSWSKY2017-26 |
| The Gansu Province Science Foundation for Distinguished Young Scholars |
1606RJDA317 |
| The Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province |
zdsyskfkt-201704 |
| The Foundation of The First Hospital of Lanzhou University |
ldyyyn2015-16 |
|
| Corresponding Author |
Xun Li, MD, Chief Doctor, Director, Director, Postdoc, Surgeon, The Fifth Department of General Surgery, The First Hospital of Lanzhou University, The First Hospital of Lanzhou University, DongGang West Road No.1, Lanzhou 730000, Gansu, China., Lanzhou 730000, Gansu Province, China. lxdr21@126.com |
| Key Words |
Biomarker; MicroRNA; Plasma; Early gastric cancer |
| Core Tip |
Early gastric cancer (EGC) has no typical symptoms and difficulty to diagnosis. We filtrated the differentially expressed microRNAs (miRNAs) in the plasma of EGC, advanced gastric cancer and benign gastritis by miRNA chip analysis. Then, reverse transcription quantitative real-time polymerase chain reaction confirmed the relative transcription level of target miRNAs. The 5 plasma miRNAs can be used as new potential biomarkers for the diagnosis of EGC. |
| Publish Date |
2019-04-04 03:01 |
| Citation |
Zhu XL, Ren LF, Wang HP, Bai ZT, Zhang L, Meng WB, Zhu KX, Ding FH, Miao L, Yan J, Wang YP, Liu YQ, Zhou WC, Li X. Plasma microRNAs as potential new biomarkers for early detection of early gastric cancer. World J Gastroenterol 2019; 25(13): 1580-1591 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i13/1580.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i13.1580 |
