ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Permissions |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Accuracy of multi-echo Dixon sequence in quantification of hepatic steatosis in Chinese children and adolescents
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yu-Zhen Zhao, Yun-Gen Gan, Jian-Li Zhou, Jia-Qi Liu, Wei-Guo Cao, Shu-Mei Cheng, Da-Ming Bai, Meng-Zhu Wang, Fang-Qin Gao and Shao-Ming Zhou |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Shenzhen Science Technology Research & Development Fund from Shenzhen Science Technology and Innovation Commission, Shenzhen, Guangdong, China |
No. CXZZ20150529144041624 |
Shenzhen Science Technology Research & Development Fund from Shenzhen Science Technology and Innovation Commission, Shenzhen, Guangdong, China |
No. JCYJ20160429174706491 |
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Corresponding Author |
Shao-Ming Zhou, MD, Chief Doctor, Department of Gastroenterology, Shenzhen Children's Hospital, 7019 Yitian Road, Shenzhen 518038, Guangdong Province, China. zhousm15d@aliyun.com |
Key Words |
Nonalcoholic fatty liver disease; Magnetic resonance imaging; Magnetic resonance spectroscopy; Children and adolescents; Hepatic steatosis |
Core Tip |
Magnetic resonance spectroscopy (MRS) is thought to be the noninvasive gold standard in the quantification of hepatic steatosis. The present study investigated the accuracy of MR imaging (MRI) in quantifying liver fat content in Chinese children and adolescents, with MRS as a reference. MRI and MRS were performed with multi-echo Dixon and HISTO sequences, respectively, to calculate hepatic proton density fat fraction. Multi-echo Dixon shows excellent correlation and agreement with MRS in quantifying liver fat content, indicating that it could be a potential tool to detect hepatic steatosis in Chinese children and adolescents. |
Publish Date |
2019-03-28 09:14 |
Citation |
Zhao YZ, Gan YG, Zhou JL, Liu JQ, Cao WG, Cheng SM, Bai DM, Wang MZ, Gao FQ, Zhou SM. Accuracy of multi-echo Dixon sequence in quantification of hepatic steatosis in Chinese children and adolescents. World J Gastroenterol 2019; 25(12): 1513-1523 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i12/1513.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i12.1513 |