Publication Name	World Journal of Methodology
Manuscript ID	4528
Country	Belgium

Received	2013-07-03 17:02
Peer-Review Started	2013-07-03 17:57
To Make the First Decision	2013-07-12 15:36
Return for Revision	2013-07-12 16:30
Revised
Second Decision	2013-08-16 19:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-17 00:16
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-27 12:23
Publish the Manuscript Online	2013-10-08 10:59

ISSN	2222-0682 (online)
Open Access
Copyright
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Autobiography
Article Title	Bifunctional staining for ex vivo determination of area at risk in rabbits with reperfused myocardial infarction
Manuscript Source	Invited Manuscript
All Author List	Yuanbo Feng, Zhan-Long Ma, Feng Chen, Jie Yu, Marlein Miranda Cona, Yi Xie, Yue Li and Yicheng Ni
Funding Agency and Grant Number	Funding Agency Grant Number KU Leuven Molecular Small Animal Imaging Center MoSAIC KUL EF/05/08 Center of Excellence in vivo Molecular Imaging Research (IMIR) of KU Leuven EU Project Asia-Link CfP 2006-Europe Aid/123738/C/ACT/Multi-Proposal 128-498/111 Jiangsu Province Natural Science Foundation, China BK2010594
Corresponding Author	Yicheng Ni, MD, PhD, Professor, Radiology Section, University Hospitals, KU Leuven Herestraat 49, 3000 Leuven, Belgium. yicheng.ni@med.kuleuven.be
Key Words	Reperfused; Acute myocardial infarction; Rabbit model; Cardiac magnetic resonance imaging; Oil-red-o dye; Iodized oil
Core Tip	For developing therapeutic procedures/drugs aimed at modulating infarct size after coronary artery disease, it is important not only to measure myocardial infarction but also to know the extent of area at risk (AAR). However, determination of the AAR both in vivo and ex vivo can be challenging, and controversial. In this experiment we sought to develop a reliable method to accurately localize the culprit coronary occlusion for postmortem verification after in vivo cardiac magnetic resonance imaging and to establish a new bifunctional staining as a standard reference for ex vivo area at risk identification, which may substantially contribute to translational cardiac imaging research.
Publish Date	2013-10-08 10:59
Citation	Feng Y, Ma ZL, Chen F, Yu J, Cona MM, Xie Y, Li Y, Ni Y. Bifunctional staining for ex vivo determination of area at risk in rabbits with reperfused myocardial infarction. World J Methodol 2013; 3(3): 27-38
URL	http://www.wjgnet.com/2222-0682/full/v3/i3/27.htm
DOI	http://dx.doi.org/10.5662/wjm.v3.i3.27

Full Article (PDF)	WJM-3-27.pdf
Manuscript File	4528-Review.docx
Answering Reviewers	4528-Answering reviewers.pdf
Copyright License Agreement	4528-Copyright assignment.pdf
Peer-review Report	4528-Peer review(s).pdf
Scientific Editor Work List	4528-Scientific editor work list.doc