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Articles Published Processes
4/18/2019 5:48:09 AM | Browse: 941 | Download: 1734
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Received |
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2018-12-27 01:15 |
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Peer-Review Started |
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2018-12-27 02:51 |
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To Make the First Decision |
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2019-01-18 07:41 |
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Return for Revision |
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2019-01-18 09:20 |
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Revised |
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2019-02-17 14:59 |
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Second Decision |
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2019-02-22 09:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-02-23 05:16 |
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Articles in Press |
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2019-02-23 05:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-03-04 14:31 |
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Typeset the Manuscript |
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2019-04-17 00:58 |
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Publish the Manuscript Online |
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2019-04-18 05:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Mechanism of exosomal microRNA-224 in the development of hepatocellular carcinoma and an evaluation of its diagnostic value
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yao Cui, Hai-Feng Xu, Ming-Yue Liu, Yu-Jie Xu, Jun-Chuan He, Yun Zhou and Shun-Dong Cang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific and Technological Research Projects of Henan Province |
162102310024 |
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| Corresponding Author |
Shun-Dong Cang, MD, Associate Professor, Doctor, Doctor, Department of Oncology, Henan Key Laboratory for Precision Medicine in cancer, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, School of Clinical Medicine, Henan University, No. 7 Weiwu Road, Zhengzhou 450003, Henan Province, China. cangshundonghn@126.com |
| Key Words |
Hepatocellular carcinoma; Serum; Exosome; MicroRNA-224; Biomarker |
| Core Tip |
We aimed to understand the mechanism of exosomal microRNA-224 (miR-224) in the development of hepatocellular carcinoma (HCC) and to evaluate its diagnostic and prognostic value for HCC patients. By directly targeting the 3'UTR of glycine N-methyltransferase, exosomal miR-224 inhibits its expression to promote proliferation and invasion. In addition, serum exosomal miR-224 also has potential diagnostic and prognostic value for HCC. |
| Publish Date |
2019-04-18 05:48 |
| Citation |
Cui Y, Xu HF, Liu MY, Xu YJ, He JC, Zhou Y, Cang SD. Mechanism of exosomal microRNA-224 in the development of hepatocellular carcinoma and an evaluation of its diagnostic value. World J Gastroenterol 2019; 25(15): 1890-1898 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i15/1890.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i15.1890 |
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