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Articles Published Processes
5/6/2019 2:06:54 AM | Browse: 823 | Download: 1596
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Received |
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2019-01-09 09:19 |
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Peer-Review Started |
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2019-01-10 03:26 |
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To Make the First Decision |
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2019-02-26 07:54 |
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Return for Revision |
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2019-02-26 09:02 |
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Revised |
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2019-03-20 07:05 |
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Second Decision |
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2019-04-04 08:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-04-10 22:05 |
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Articles in Press |
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2019-04-10 22:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-04-22 08:00 |
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Publish the Manuscript Online |
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2019-05-06 02:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Hui Yang, Yu-xiang Zhang, Yang Gui, Jiang-Bo Liu, Jun-Jun Sun and Hua Fan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
U1504815 |
| the National Natural Science Foundation of China |
U1504808 |
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| Corresponding Author |
Hua Fan, PhD, Academic Fellow, First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, No. 24 Jing-Hua Road, Luoyang 471003, Henan Province, China. fanhua19851229@haust.edu.cn |
| Key Words |
Pancreatic cancer; Autophagy-related protein microtubule-associated protein 1A/1B-light chain 3; Perineural invasion; Gene Ontology analysis; Kyoto Encyclopedia of Genes and Genomes pathway analysis; Ubiquitin C |
| Core Tip |
In this study, we identified differentially expressed genes based on the autophagy-related protein microtubule-associated protein 1A/1B-light chain 3 (LC3) to analyze the gene expression profile of autophagy in pancreatic cancer. Three hundred and forty-seven genes that have no confirmed association with the autophagy process of human pancreatic cancer cells in previous studies were concentrated, and the key pathways involved in autophagy were enriched. Furthermore, a key gene ubiquitin C which is closely related to the occurrence of perineural invasion (PNI) was determined, suggesting that LC3 may influence the PNI and prognosis of pancreatic cancer through ubiquitin C. |
| Publish Date |
2019-05-06 02:06 |
| Citation |
Yang YH, Zhang YX, Gui Y, Liu JB, Sun JJ, Fan H. Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3. World J Gastroenterol 2019; 25(17): 2086-2098 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i17/2086.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i17.2086 |
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