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Articles Published Processes
5/28/2019 10:20:54 AM | Browse: 1049 | Download: 1668
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Received |
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2019-02-16 14:46 |
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Peer-Review Started |
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2019-02-18 02:36 |
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To Make the First Decision |
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2019-03-18 06:10 |
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Return for Revision |
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2019-03-26 02:45 |
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Revised |
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2019-04-05 15:25 |
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Second Decision |
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2019-05-16 07:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-22 05:39 |
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Articles in Press |
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2019-05-22 05:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-05-28 06:24 |
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Publish the Manuscript Online |
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2019-05-28 10:20 |
ISSN |
1949-8470 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Observational Study |
Article Title |
Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging
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Manuscript Source |
Invited Manuscript |
All Author List |
Keren Bachi, Venkatesh Mani, Audrey E Kaufman, Nadia Alie, Rita Z Goldstein, Zahi A Fayad and Nelly Alia-Klein |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
NIDA |
K23DA045928-01 |
NIDA |
R01DA041528 |
NIH/NHLBI |
R01 HL071021 |
TMII |
Internal funding |
American Heart Association Grant in Aid |
17GRNT33420119 |
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Corresponding Author |
Nelly Alia-Klein, PhD, Associate Professor, Departments of Psychiatry & Neuroscience, Icahn School of Medicine at Mount Sinai, One Gustave Levy, New York, NY 10029, United States. nelly.alia-klein@mssm.edu |
Key Words |
3-D dark-blood magnetic resonance imaging; 18F-fluorodeoxyglucose positron emission tomography; Simultaneous positron emission tomography; Magnetic resonance; Substance use disorder; Cocaine addiction; Atherosclerosis; Plaque burden; Vascular inflammation |
Core Tip |
Despite undetected clinical signs, cocaine use increases risk of stroke, coronary artery disease and myocardial infarction. Simultaneous carotid positron emission tomography/magnetic resonance imaging can effectively evaluate vascular inflammation and plaque burden in individuals with cocaine use disorder. Cocaine users had increased wall area, comparable to individuals with cardiovascular risk and significantly higher than healthy controls. Wall area in cocaine users positively correlated with greater cocaine withdrawal and craving. Broader trials are warranted to develop protocols for early detection of cardiovascular risk and preventive intervention in individuals with cocaine use disorder. |
Publish Date |
2019-05-28 10:20 |
Citation |
Bachi K, Mani V, Kaufman AE, Alie N, Goldstein RZ, Fayad ZA, Alia-Klein N. Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging. World J Radiol 2019;11(5): 62-73 |
URL |
URL: https://www.wjgnet.com/1949-8470/full/v11/i5/62.htm |
DOI |
DOI: https://dx.doi.org/10.4329/wjr.v11.i5.62 |
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