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5/28/2019 10:20:54 AM | Browse: 142 | Download: 163
Publication Name World Journal of Radiology
Manuscript ID 45529
Country/Territory United States
2019-02-16 14:46
Peer-Review Started
2019-02-18 02:36
To Make the First Decision
2019-03-18 06:10
Return for Revision
2019-03-26 02:45
2019-04-05 15:25
Second Decision
2019-05-16 07:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-22 05:39
Articles in Press
2019-05-22 05:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-05-28 06:24
Publish the Manuscript Online
2019-05-28 10:20
ISSN 1949-8470 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac and Cardiovascular Systems
Manuscript Type Observational Study
Article Title Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging
Manuscript Source Invited Manuscript
All Author List Keren Bachi, Venkatesh Mani, Audrey E Kaufman, Nadia Alie, Rita Z Goldstein, Zahi A Fayad and Nelly Alia-Klein
Author(s) ORCID Number
Keren Bachi http://orcid.org/0000-0001-9817-5957
Venkatesh Mani http://orcid.org/0000-0002-0432-2918
Audrey E Kaufman http://orcid.org/0000-0002-9221-9004
Nadia Alie http://orcid.org/0000-0002-0626-7393
Rita Z Goldstein http://orcid.org/0000-0002-1127-028X
Zahi A Fayad http://orcid.org/0000-0002-3439-7347
Nelly Alia-Klein http://orcid.org/0000-0003-1876-8133
Funding Agency and Grant Number
Funding Agency Grant Number
NIDA K23DA045928-01
NIDA R01DA041528
NIH/NHLBI R01 HL071021
TMII Internal funding
American Heart Association Grant in Aid 17GRNT33420119
Corresponding author Nelly Alia-Klein, PhD, Associate Professor, Associate Professor, Departments of Psychiatry & Neuroscience, Icahn School of Medicine at Mount Sinai, One Gustave Levy, New York, NY10029, United States. nelly.alia-klein@mssm.edu
Keywords 3-D dark-blood magnetic resonance imaging; 18F-fluorodeoxyglucose positron emission tomography; Simultaneous positron emission tomography; Magnetic resonance; Substance use disorder; Cocaine addiction; Atherosclerosis; Plaque burden; Vascular inflammation
Core Tip Despite undetected clinical signs, cocaine use increases risk of stroke, coronary artery disease and myocardial infarction. Simultaneous carotid positron emission tomography/magnetic resonance imaging can effectively evaluate vascular inflammation and plaque burden in individuals with cocaine use disorder. Cocaine users had increased wall area, comparable to individuals with cardiovascular risk and significantly higher than healthy controls. Wall area in cocaine users positively correlated with greater cocaine withdrawal and craving. Broader trials are warranted to develop protocols for early detection of cardiovascular risk and preventive intervention in individuals with cocaine use disorder.
Publish Date 2019-05-28 10:20
Citation Bachi K, Mani V, Kaufman AE, Alie N, Goldstein RZ, Fayad ZA, Alia-Klein N. Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging. World J Radiol 2019;11(5): 62-73
Url URL: https://www.wjgnet.com/1949-8470/full/v11/i5/62.htm
DOI DOI: https://dx.doi.org/10.4329/wjr.v11.i5.62
Full Article (PDF) WJR-11-62.pdf
Full Article (Word) WJR-11-62.docx
Manuscript File 45529-Review.docx
Answering Reviewers 45529-Answering reviewers.pdf
Audio Core Tip 45529-Audio core tip.m4a
Biostatistics Review Certificate 45529-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 45529-Conflict-of-interest statement.pdf
Copyright License Agreement 45529-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45529-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 45529-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 45529-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 45529-Language certificate.pdf
Peer-review Report 45529-Peer-review(s).pdf
Scientific Misconduct Check 45529-Scientific misconduct check.pdf
Scientific Editor Work List 45529-Scientific editor work list.pdf