Publication Name	World Journal of Gastroenterology
Manuscript ID	4559
Country	China

Received	2013-07-06 11:15
Peer-Review Started	2013-07-06 17:57
To Make the First Decision	2013-09-02 16:00
Return for Revision	2013-09-05 10:58
Revised	2013-12-31 12:35
Second Decision	2014-02-20 08:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 09:38
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-12 13:31
Typeset the Manuscript	2014-03-27 16:41
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Autobiography
Article Title	HBsAg levels in HBeAg-positive chronic hepatitis B patients with different immune conditions
Manuscript Source	Invited Manuscript
All Author List	Yi-Min Zhang, Yi-Da Yang, Hong-Yu Jia, Lin-Yan Zeng, Wei Yu, Ning Zhou and Lan-Juan Li
Funding Agency and Grant Number	Funding Agency Grant Number China National Science and Technology Major Project 2012ZX10002004 China National Science and Technology Major Project 2013ZX10002001 National High-tech R&D Program of China (863 Program) 2011AA020104 Zhejiang CTM Science and Technology Project 2011ZB061
Corresponding Author	Lan-Juan Li, MD, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. ljli@zju.edu.cn
Key Words	Chronic hepatitis B; Hepatitis B surface antigen; Hepatitis B e antigen; Immune tolerance; Immune clearance; Acute on chronic liver failure
Core Tip	This study showed that a dramatic immune response demonstrated that acute on chronic liver failure results in lower serum hepatitis B surface antigen levels compared with a mild immune response in patients in the immune clearance phase. These findings may have important implications for understanding the immune clearance of hepatitis B virus in these patients.
Publish Date	2014-04-17 13:27
Citation	Zhang YM, Yang YD, Jia HY, Zeng LY, Yu W, Zhou N, Li LJ. HBsAg levels in HBeAg-positive chronic hepatitis B patients with different immune conditions. World J Gastroenterol 2014; 20(15): 4407-4413
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4407.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4407

Full Article (PDF)	WJG-20-4407.pdf
Full Article (Word)	WJG-20-4407.doc
Manuscript File	4559-Review.doc
Answering Reviewers	4559-Answering reviewer(s).pdf
Copyright License Agreement	4559-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4559-Language certificate.pdf
Peer-review Report	4559-Peer reviewer(s).pdf
Scientific Editor Work List	4559-Scientific editor work list.doc