BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/6/2019 2:06:54 AM | Browse: 838 | Download: 1617
Publication Name World Journal of Gastroenterology
Manuscript ID 45619
Country/Territory China
Received
2019-01-13 05:31
Peer-Review Started
2019-01-14 07:25
To Make the First Decision
2019-02-14 02:12
Return for Revision
2019-02-14 05:21
Revised
2019-03-13 01:20
Second Decision
2019-03-15 09:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-16 17:56
Articles in Press
2019-03-16 17:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-03-28 01:23
Typeset the Manuscript
2019-04-26 08:50
Publish the Manuscript Online
2019-05-06 02:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Herbs-partitioned moxibustion alleviates aberrant cell apoptosis of the intestinal epithelium by upregulating A20 expression in a mouse model of Crohn’s disease
Manuscript Source Unsolicited Manuscript
All Author List Jing Zhou, Lu-Yi Wu, Liu Chen, Ya-Jing Guo, Yi Sun, Tao Li, Ji-Meng Zhao, Chun-Hui Bao, Huan-Gan Wu and Yin Shi
ORCID
Author(s) ORCID Number
Jing Zhou http://orcid.org/0000-0003-0495-2175
Lu-Yi Wu http://orcid.org/0000-0002-7297-2509
Liu Chen http://orcid.org/0000-0003-3853-6612
Ya-Jing Guo http://orcid.org/0000-0003-0627-9236
Yi Sun http://orcid.org/0000-0001-7705-219X
Tao Li http://orcid.org/0000-0001-6313-3829
Ji-Meng Zhao http://orcid.org/0000-0001-9075-6036
Chun-Hui Bao http://orcid.org/0000-0002-9763-0046
Huan-Gan Wu http://orcid.org/0000-0003-1725-6881
Yin Shi http://orcid.org/0000-0002-7502-1573
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China No. 81273844, 81473757
the National Key Basic Research Program of China No.2015CB554500
the Shanghai Rising-Star Program No.16QA1403400
Corresponding Author Yin Shi, PhD, Doctor, Professor, Outpatient Department, Shanghai Institute of Acupuncture-Moxibustion and Meridian, 650 South Wanping Road, Shanghai 200030, China. flysy0636@163.com
Key Words Herbs-partitioned moxibustion; Crohn’s disease; Apoptotic pathway; Inflammation; A20
Core Tip We report our results derived from intestinal epithelial cell A20 deletion mice in Crohn’s disease. The Crohn’s disease model was induced by 2, 4, 6 trinitrobenzene sulfonic acid. This study demonstrates for the first time that herbs-partitioned moxibustion can upregulate expression of A20, resulting in downregulation of tumor necrosis factor receptor (TNFR) 1, TNFR1-associated death domain and receptor-interacting protein 1 to alleviate increased cell apoptosis in the intestinal epithelial barrier in Crohn's disease.
Publish Date 2019-05-06 02:06
Citation Zhou J, Wu LY, Chen L, Guo YJ, Sun Y, Li T, Zhao JM, Bao CH, Wu HG and Shi Y. Herbs-partitioned moxibustion alleviates aberrant cell apoptosis of the intestinal epithelium by upregulating A20 expression in a mouse model of Crohn’s disease. World J Gastroenterol 2019; 25(17): 2071-2085
URL https://www.wjgnet.com/1007-9327/full/v25/i17/2071.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i17.2071
Full Article (PDF) WJG-25-2071.pdf
The ARRIVE Guidelines 45619-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 45619-Review_Edited.doc
Answering Reviewers 45619-Answering reviewers.pdf
Audio Core Tip 45619-Audio core tip.MP3
Biostatistics Review Certificate 45619-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 45619-Conflict-of-interest statement.pdf
Copyright License Agreement 45619-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45619-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 45619-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 45619-Language certificate.pdf
Peer-review Report 45619-Peer-review(s).pdf
Scientific Misconduct Check 45619-Google-MA RY-1.png
Scientific Misconduct Check 45619-Google-MA RY-2.png
Scientific Misconduct Check 45619-Scientific misconduct check.pdf
Scientific Editor Work List 45619-Scientific editor work list.pdf