BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/6/2019 2:06:54 AM | Browse: 937 | Download: 2072
 |
Received |
|
2019-01-13 05:31 |
|
Peer-Review Started |
|
2019-01-14 07:25 |
|
To Make the First Decision |
|
2019-02-14 02:12 |
|
Return for Revision |
|
2019-02-14 05:21 |
|
Revised |
|
2019-03-13 01:20 |
|
Second Decision |
|
2019-03-15 09:27 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2019-03-16 17:56 |
|
Articles in Press |
|
2019-03-16 17:56 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2019-03-28 01:23 |
|
Typeset the Manuscript |
|
2019-04-26 08:50 |
|
Publish the Manuscript Online |
|
2019-05-06 02:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Herbs-partitioned moxibustion alleviates aberrant cell apoptosis of the intestinal epithelium by upregulating A20 expression in a mouse model of Crohn’s disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing Zhou, Lu-Yi Wu, Liu Chen, Ya-Jing Guo, Yi Sun, Tao Li, Ji-Meng Zhao, Chun-Hui Bao, Huan-Gan Wu and Yin Shi |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
No. 81273844, 81473757 |
| the National Key Basic Research Program of China |
No.2015CB554500 |
| the Shanghai Rising-Star Program |
No.16QA1403400 |
|
| Corresponding Author |
Yin Shi, PhD, Doctor, Doctor, Professor, Outpatient Department, Shanghai Institute of Acupuncture-Moxibustion and Meridian, 650 South Wanping Road, Shanghai 200030, China. flysy0636@163.com |
| Key Words |
Herbs-partitioned moxibustion; Crohn’s disease; Apoptotic pathway; Inflammation; A20 |
| Core Tip |
We report our results derived from intestinal epithelial cell A20 deletion mice in Crohn’s disease. The Crohn’s disease model was induced by 2, 4, 6 trinitrobenzene sulfonic acid. This study demonstrates for the first time that herbs-partitioned moxibustion can upregulate expression of A20, resulting in downregulation of tumor necrosis factor receptor (TNFR) 1, TNFR1-associated death domain and receptor-interacting protein 1 to alleviate increased cell apoptosis in the intestinal epithelial barrier in Crohn's disease. |
| Publish Date |
2019-05-06 02:06 |
| Citation |
Zhou J, Wu LY, Chen L, Guo YJ, Sun Y, Li T, Zhao JM, Bao CH, Wu HG and Shi Y. Herbs-partitioned moxibustion alleviates aberrant cell apoptosis of the intestinal epithelium by upregulating A20 expression in a mouse model of Crohn’s disease. World J Gastroenterol 2019; 25(17): 2071-2085 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i17/2071.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i17.2071 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
