Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	45743
Country	Australia

Received	2019-01-16 08:05
Peer-Review Started	2019-01-17 10:17
To Make the First Decision	2019-01-27 05:42
Return for Revision	2019-01-27 07:35
Revised	2019-02-01 01:41
Second Decision	2019-02-22 04:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-02-22 06:28
Articles in Press	2019-02-22 06:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-02-23 09:12
Publish the Manuscript Online	2019-02-26 08:24

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Case Report
Article Title	Acquired segmental colonic hypoganglionosis in an adult Caucasian male: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Allan Mun Fai Kwok, Andrew B Still and Kimberly Hart
ORCID	Author(s) ORCID Number Allan Mun Fai Kwok http://orcid.org/0000-0002-8742-6236 Andrew B Still http://orcid.org/0000-0003-1954-1854 Kimberly Hart http://orcid.org/0000-0001-5986-6229
Funding Agency and Grant Number
Corresponding Author	Allan Mun Fai Kwok, MBBS, Doctor, Doctor, Lecturer, Surgeon, Department of Surgery, Wollongong Hospital, Locked Bag 8808, South Coast Mail Centre, Wollongong 2500, NSW, Australia. amf.kwok@gmail.com
Key Words	Acquired hypoganglionosis; Hirschprung’s disease; Adult; Ganglion cells; Acetylcholinesterase; Calretinin; Case report
Core Tip	We describe the rare case of a 31 year-old man who presented with severe abdominal pain, haematochezia and a recent change in bowel habits who was found to have colitis affecting the transverse, descending and sigmoid colon on computed tomography. Despite an exhaustive panel of investigations no definite cause could be found for this. Partial colectomy was performed due to failure of medical management and histological examination revealed segmental hypoganglionosis. Previous reports in the literature have proposed the possible role of infective, autoimmune or ischaemic conditions in inciting a pathological chronic inflammatory response with resultant ganglionic destruction.
Publish Date	2019-02-26 08:24
Citation	Kwok AM, Still AB, Hart K. Acquired segmental colonic hypoganglionosis in an adult Caucasian male: A case report. World J Gastrointest Surg 2019; 11(2): 101-111
URL	https://www.wjgnet.com/1948-9366/full/v11/i2/101.htm
DOI	https://dx.doi.org/10.4240/wjgs.v11.i2.101

Full Article (PDF)	WJGS-11-101.pdf
Full Article (Word)	WJGS-11-101.docx
Manuscript File	45743-Review.doc
Answering Reviewers	45743-Answering reviewers.pdf
Audio Core Tip	45743-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	45743-Conflict-of-interest statement.pdf
Copyright License Agreement	45743-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	45743-Informed consent statement.pdf
Peer-review Report	45743-Peer-review(s).pdf
Scientific Misconduct Check	45743-Scientific misconduct check.pdf
Scientific Editor Work List	45743-Scientific editor work list.pdf
CrossCheck Report	45743-CrossCheck report.pdf