BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/18/2019 5:48:09 AM | Browse: 934 | Download: 2237
 |
Received |
|
2019-01-24 01:46 |
|
Peer-Review Started |
|
2019-01-24 07:18 |
|
First Decision by Editorial Office Director |
|
2019-02-26 07:00 |
|
Return for Revision |
|
2019-02-26 09:00 |
|
Revised |
|
2019-03-20 14:48 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2019-03-22 08:19 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2019-03-25 04:43 |
|
Articles in Press |
|
2019-03-25 04:43 |
|
Edit the Manuscript by Language Editor |
|
2019-04-01 13:44 |
|
Typeset the Manuscript |
|
2019-04-17 00:55 |
|
Publish the Manuscript Online |
|
2019-04-18 05:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Predictive and prognostic implications of the autophagy-related proteins 4E-binding protein 1, Beclin-1 and microtubule-associated protein 1A/B-light chain 3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gui-Fang Guo, Yi-Xing Wang, Yi-Jun Zhang, Xiu-Xing Chen, Jia-Bin Lu, Hao-Hua Wang, Chang Jiang, Hui-Quan Qiu and Liang-Ping Xia |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Gui-Fang Guo, MD, PhD, Professor, VIP Department, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510000, Guangdong Province, China. guogf@sysucc.org.cn |
| Key Words |
4E-binding protein 1; Beclin-1; Microtubule-associated protein 1A/B-light chain 3; Advanced colorectal cancer; Cetuximab efficacy; Prognosis |
| Core Tip |
Considering the response rate of cetuximab in advanced colorectal cancer patients with wild-type KRAS, autophagy might be a novel predictor to exclude patients who will not respond to cetuximab. Accordingly, Beclin1, microtubule-associated protein 1A/B-light chain 3 (LC3) and 4E-binding protein 1 (4E-BP1) were studied in this research. We found LC3 is overexpressed in tumor tissues, and the expression levels of Beclin1 and 4E-BP1 were related to overall survival. |
| Publish Date |
2019-04-18 05:48 |
| Citation |
Guo GF, Wang YX, Zhang YJ, Chen XX, Lu JB, Wang HH, Jiang C, Qiu HJ, Xia LP. Predictive and prognostic implications of the autophagy-related proteins 4E-binding protein 1, Beclin-1 and microtubule-associated protein 1A/B-light chain 3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data. World J Gastroenterol 2019; 25(15): 1840-1853
|
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i15/1840.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i15.1840 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
