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Articles Published Processes
8/7/2019 7:09:17 AM | Browse: 828 | Download: 1590
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Received |
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2019-01-17 01:44 |
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Peer-Review Started |
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2019-01-18 04:09 |
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To Make the First Decision |
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2019-01-31 07:03 |
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Return for Revision |
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2019-01-31 08:32 |
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Revised |
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2019-02-07 09:22 |
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Second Decision |
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2019-02-22 09:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-02-23 05:13 |
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Articles in Press |
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2019-02-23 05:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-05 08:09 |
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Publish the Manuscript Online |
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2019-08-07 07:09 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Management of skin toxicities during panitumumab treatment in metastatic colorectal cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Olivier Bouche, Meher Ben Abdelghani, Jean-Luc Labourey, Simon TRIBY, René-Jean Bensadoun, Thomas Jouary and Gaétan Des Guetz |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Amgen |
20090656 POPEC |
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Corresponding Author |
Olivier Bouche, MD, Professor, Department of Gastroenterology and Digestive Oncology, Hôpital Robert Debré, CHU Reims, Avenue du Général Koenig, Reims 51092, France. obouche@chu-reims.fr |
Key Words |
Metastatic colorectal cancer; Epidermal growth factor receptor inhibitors; Panitumumab; Skin toxicity; Quality of life; |
Core Tip |
Anti-epidermal growth factor receptor therapy is associated with skin adverse events not previously reported with conventional chemotherapy. Prophylactic actions are recommended, but routine clinical management of these toxicities and their impact on quality of life remain unknown. This observational study describes a cohort of patients who began treatment with panitumumab for metastatic colorectal cancer. The rates of the different skin toxicities peaked at various times and were improved at the end of the follow-up. Nevertheless, their clinical management could be optimized with a better adherence to current recommendations. The impact of skin toxicities on patient’s quality of life appeared to be limited. |
Publish Date |
2019-08-07 07:09 |
Citation |
Bouché O, Ben Abdelghani M, Labourey JL, Triby S, Bensadoun RJ, Jouary T, Des Guetz G. Management of skin toxicities during panitumumab treatment in metastatic colorectal cancer. World J Gastroenterol 2019; 25(29): 4007-4018 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i29/4007.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i29.4007 |
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