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4/18/2019 5:48:09 AM | Browse: 835 | Download: 1160
Publication Name World Journal of Gastroenterology
Manuscript ID 45885
Country China
Received
2019-01-19 07:00
Peer-Review Started
2019-01-21 01:01
To Make the First Decision
2019-02-14 01:06
Return for Revision
2019-02-15 03:58
Revised
2019-02-21 03:05
Second Decision
2019-03-01 07:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-02 03:40
Articles in Press
2019-03-02 03:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-03-31 21:03
Typeset the Manuscript
2019-04-17 00:56
Publish the Manuscript Online
2019-04-18 05:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license,which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Lysyl oxidase and hypoxia inducible factor 1α: Biomarkers of gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Ya-lin Han, Li Chen, Rui Qin, Guan-Qing Wang, Xiao-Hua Lin and Guang-Hai Dai
ORCID
Author(s) ORCID Number
Ya-lin Han http://orcid.org/0000-0003-4552-1486
Li Chen http://orcid.org/0000-0002-9671-7967
Rui Qin http://orcid.org/0000-0001-6033-4393
Guan-Qing Wang http://orcid.org/0000-0002-2269-5881
Xiao-Hua Lin http://orcid.org/0000-0002-4494-8480
Guang-Hai Dai http://orcid.org/0000-0001-7582-9348
Funding Agency and Grant Number
Funding Agency Grant Number
the grants from the Military Medical Science and Technology Youth Training Program Top-Notch Project 16QNP146
Corresponding Author Guang-Hai Dai, PhD, Professor, Department of Medical Oncology, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China. handai713@126.com
Key Words Lysyl oxidase; Hypoxia inducible factor 1α; Gastric cancer; Biomarker; Prognosis
Core Tip Lysyl oxidase (LOX) is a secreted extracellular matrix protein that plays an important role in remodeling the extracellular matrix and promotion of tumor progression. The LOX family comprises the prototypic LOX, and LOX-like proteins are involved in carcinogenesis. Hypoxia inducible factor 1α (HIF1α) is a type of transcription factor complex that has the capacity to regulate oxygen tension. In addition, HIF1α is able to activate or bind to multiple target genes and participate in inflammatory and other diseases. HIF1α accelerates the growth and metastasis of hepatocellular carcinoma.
Publish Date 2019-04-18 05:48
Citation Han YL, Chen L, Qin R, Wang GQ, Lin XH, Dai GH. Lysyl oxidase and hypoxia inducible factor 1α: Biomarkers of gastric cancer. World J Gastroenterol 2019; 25(15): 1828-1839
URL https://www.wjgnet.com/1007-9327/full/v25/i15/1828.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i15.1828
Full Article (PDF) WJG-25-1828.pdf
Manuscript File FP6794_de25_CE1MS-edit2.doc
Answering Reviewers 45885-Answering reviewers.pdf
Audio Core Tip 45885-Audio core tip.mp3
Biostatistics Review Certificate 45885-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 45885-Conflict-of-interest statement.pdf
Copyright License Agreement 45885-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45885-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 45885-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 45885-Language certificate.pdf
Peer-review Report 45885-Peer-review(s).pdf
Scientific Misconduct Check 45885-Scientific misconduct check.pdf
Scientific Editor Work List 45885-Scientific editor work list.pdf