| ISSN |
1948-0210 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Tonsil-derived stem cells as a new source of adult stem cells
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Kyung-Ah Cho, Hyun Jung Lee, Hansaem Jeong, Miri Kim, Soo Yeon Jung, Hae Sang Park, Kyung-Ha Ryu, Seung Jin Lee, Byeongmoon Jeong, Hyukjin Lee and Han Su Kim |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Ministry of Health & Welfare, Republic of Korea |
HI16C- 2207 |
| Basic Science Research Program |
2018R1D1A1A09083264 |
| BioMedical Technology Development Program |
2015M3A9D7031026 |
| Ewha Womans University |
RP-grant 2017 |
|
| Corresponding Author |
Han Su Kim, MD, PhD, Doctor, Doctor, Professor, Surgeon, Department of Otorhinolaryngology, College of Medicine, Ewha Womans University, Yangcheon-gu, Ahnyangcheon-ro 1071, Seoul 07895, South Korea. sevent@ewha.ac.kr |
| Key Words |
Stem cell; Tonsil-derived stem cell; Differentiation; Endoderm; Mesoderm; Ectoderm |
| Core Tip |
The use of adult stem cells is often limited by the lack of differentiation among stem cells isolated from certain germ layers. However, tonsil-derived stem cells (T-SCs) were able to differentiate into various tissue types from the three germ layers, which is the most advantageous feature of this new stem cell source. T-SCs can also be used as native cells in the treatment of various immune-related diseases. As a result, it can be concluded that T-SCs have great potential for clinical applications in cell therapy and regenerative medicine. |
| Publish Date |
2019-08-26 10:16 |
| Citation |
Cho KA, Lee HJ, Jeong H, Kim M, Jung SY, Park HS, Ryu KH, Lee SJ, Jeong B, Lee H, Kim HS. Tonsil-derived stem cells as a new source of adult stem cells. World J Stem Cell 2019; 11(8):506-518 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i8/506.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i8.506 |
