Publication Name	World Journal of Transplantation
Manuscript ID	4600
Country	United States

Received	2013-07-10 09:36
Peer-Review Started	2013-07-10 10:11
To Make the First Decision	2013-08-08 11:25
Return for Revision	2013-08-20 09:56
Revised	2013-08-24 02:09
Second Decision	2013-09-05 11:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-05 13:04
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-13 19:53
Publish the Manuscript Online	2013-12-31 17:17

ISSN	2220-3230 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Minireviews
Article Title	Essential concept of transplant immunology for clinical practice
Manuscript Source	Invited Manuscript
All Author List	Damodar Kumbala and Rubin Zhang
Funding Agency and Grant Number
Corresponding Author	Rubin Zhang, MD, FASN, Professor of Clinical Medicine, Section of Nephrology, Department of Medicine, Tulane University School of Medicine, 1430 Tulane Ave, SL-45, New Orleans, LA 70112, United States. rzhang@tulane.edu
Key Words	Alloimmune response; Major histocompatibility complex; Human leukocyte antigens; Co-stimulation pathway; Panel reactive antibody; Donor specific antibody; Non-human leukocyte antigens antibody; Crossmatch
Core Tip	Core tip: The alloimmune response is initiated by T-cell recognition of alloantigens through direct or indirect pathways. Three signal models have been established during T-cell activation, which subsequently produces various effector T-cells and antibody production. Sensitive crossmatch is routinely performed before kidney transplant to detect any significant donor-specific antibodies, so that hyperacute rejection can be eliminated. Solid phase based Luminex assay can further characterize human leukocyte antigens antibodies before and after kidney transplant to guide our clinical practice.
Publish Date	2013-12-31 17:17
Citation	Kumbala D, Zhang R. Essential concept of transplant immunology for clinical practice. World J Transplant 2013; 3(4): 113-118
URL	http://www.wjgnet.com/2220-3230/full/v3/i4/113.htm
DOI	http://dx.doi.org/10.5500/wjt.v3.i4.113

Full Article (PDF)	WJT-3-113.pdf
Full Article (Word)	WJT-3-113.doc
Manuscript File	4600-Review.doc
Answering Reviewers	4600-Answering reviewers.pdf
Copyright License Agreement	4600-Copyright assignment.pdf
Peer-review Report	4600-Peer reviews.pdf
Scientific Editor Work List	4600-Scientific editor work list.doc