Publication Name	World Journal of Gastroenterology
Manuscript ID	4606
Country	China

Received	2013-07-10 10:11
Peer-Review Started	2013-07-10 10:32
To Make the First Decision	2013-07-26 18:44
Return for Revision	2013-07-29 11:32
Revised	2013-08-04 13:24
Second Decision	2013-08-20 10:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-20 13:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-09 18:08
Publish the Manuscript Online	2013-11-08 14:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Effects of integrin-targeted photodynamic therapy on pancreatic carcinoma cell
Manuscript Source	Invited Manuscript
All Author List	Min Zhou, Qian-Wen Ni, Shan-Ying Yang, Chun-Ying Qu, Peng-Cheng Zhao, Jian-Cheng Zhang and Lei-Ming Xu
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Municipal Health Bureau principal project 210009 (to Xu LM) Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition 11DZ2260500
Corresponding Author	Dr. Lei-Ming Xu, Chief Physician, Digestive Endoscopic Diagnosis and Treatment Center, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China. leiming.xu@aliyun.com
Key Words	Pancreatic carcinoma; Targeted probe; Photodynamic therapy; Apoptosis; Reactive oxygen species
Core Tip	Arginine-glycine-aspartic acid (RGD), sequence of small peptide, is an integrin antagonist. Quantum dots are characterized by conjugation with antibodies, peptides, or small molecules. Therefore, the construction of RGD-coupled quantum dots fluorescence probe allows for successful combination to integrin. Photodynamic therapy with a quantum dots-RGD probe, as a photosensitizer, significantly inhibits cell proliferation and increases apoptosis in SW1990 cells.
Publish Date	2013-11-08 14:06
Citation	Zhou M, Ni QW, Yang SY, Qu CY, Zhao PC, Zhang JC, Xu LM. Effects of integrin-targeted photodynamic therapy on pancreatic carcinoma cell. World J Gastroenterol 2013; 19(39): 6559-6567
URL	http://www.wjgnet.com/1007-9327/full/v19/i39/6559.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i39.6559

Full Article (PDF)	WJG-19-6559.pdf
Manuscript File	4606-Review.doc
Answering Reviewers	4606-Answering reviewers.pdf
Copyright License Agreement	4606-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4606-Language certificate.pdf
Peer-review Report	4606-Peer reviews.pdf
Scientific Editor Work List	4606-Scientific editor work list.doc