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Articles Published Processes
6/28/2019 9:19:59 AM | Browse: 907 | Download: 1653
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Received |
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2019-02-06 04:03 |
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Peer-Review Started |
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2019-02-12 05:02 |
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To Make the First Decision |
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2019-03-18 06:33 |
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Return for Revision |
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2019-03-26 11:25 |
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Revised |
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2019-03-26 23:19 |
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Second Decision |
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2019-05-10 08:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-14 10:06 |
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Articles in Press |
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2019-05-14 10:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-06-24 01:53 |
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Publish the Manuscript Online |
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2019-06-28 09:19 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Proton pump inhibitors and adverse effects in kidney transplant recipients: A meta-analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Boonphiphop Boonpheng, Charat Thongprayoon, Tarun Bathini, Konika Sharma, Michael A Mao and Wisit Cheungpasitporn |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wisit Cheungpasitporn, MD, Assistant Professor, Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 N. State St., Jackson, MS 39216, United States. wcheungpasitporn@gmail.com |
| Key Words |
Proton pump inhibitors; Kidney; Renal transplantation; Meta-analysis hypomagnesemia; Systematic reviews |
| Core Tip |
Several pharmacokinetic studies have raised concerns regarding the interaction between proton pump inhibitors (PPIs) and immunosuppressive drugs in transplant patients. Whether the adverse effects of PPIs have a clinical significance in kidney transplant recipients remains unclear. We performed this meta-analysis to assess the risk of adverse effects in kidney transplant recipients on PPI compared with those without PPI exposure. We demonstrate that PPI use is not associated with significant risks of higher acute rejection, graft loss, or 1-year mortality. However, PPI use is associated with 1.56-fold increased risk of hypomagnesemia. Thus, future studies are needed to assess the impact of PPIs on long-term outcomes. |
| Publish Date |
2019-06-28 09:19 |
| Citation |
Boonpheng B, Thongprayoon C, Bathini T, Sharma K, Mao MA, Cheungpasitporn W. Proton pump inhibitors and adverse effects in kidney transplant recipients: A meta-analysis. World J Transplantation 2019; 9(2): 35-47 |
| URL |
https://www.wjgnet.com/2220-3230/full/v9/i2/35.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v9.i2.35 |
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