Publication Name	World Journal of Gastroenterology
Manuscript ID	4631
Country	China

Received	2013-07-12 08:31
Peer-Review Started	2013-07-12 09:13
To Make the First Decision	2013-08-08 11:22
Return for Revision	2013-08-15 09:11
Revised	2013-08-28 17:31
Second Decision	2013-09-05 11:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-05 13:08
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-29 11:53
Publish the Manuscript Online	2013-11-16 18:29

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Gastrointestinal complications of systemic sclerosis
Manuscript Source	Invited Manuscript
All Author List	Xin-Ping Tian and Xuan Zhang
Funding Agency and Grant Number
Corresponding Author	Xuan Zhang, Professor, Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No.1 Shuai Fu Yuan, Dongcheng District, Beijing 100730, China. zxpumch2003@sina.com
Key Words	Systemic sclerosis; Gastrointestinal tract; Manometry; Endoscopy; Diagnosis; Treatment
Core Tip	Although often overlooked by clinicians, the gastrointestinal tract is the most commonly damaged system in patients with progressive systemic sclerosis. Virtually all parts of the gastrointestinal tract can be involved, although the esophagus is the most frequently reported. The mechanisms of gastrointestinal tract involvement have not been clarified; however, vascular damage, excessive accumulation of collagen, and immunological abnormalities may play a role because they are the most frequent histological findings in biopsies and autopsies. Non-specific symptoms, including dyspepsia, nausea, vomiting, and abdominal distension are common complaints. Although supportive and symptomatic treatment is the main therapeutic strategy for systemic sclerosis, early diagnosis is critical for improving patient prognosis.
Publish Date	2013-11-16 18:29
Citation	Tian XP, Zhang X. Gastrointestinal complications of systemic sclerosis. World J Gastroenterol 2013; 19(41): 7062-7068
URL	http://www.wjgnet.com/1007-9327/full/v19/i41/7062.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i41.7062

Full Article (PDF)	WJG-19-7062.pdf
Manuscript File	4631-Review.doc
Answering Reviewers	4631-Answering reviewers.pdf
Copyright License Agreement	4631-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4631-Language certificate.pdf
Peer-review Report	4631-Peer review.pdf
Scientific Editor Work List	4631-Scientific editor work list.doc