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Articles Published Processes
5/27/2019 8:24:36 AM | Browse: 974 | Download: 1615
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Received |
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2019-03-04 07:15 |
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Peer-Review Started |
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2019-03-05 01:48 |
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To Make the First Decision |
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2019-03-21 05:53 |
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Return for Revision |
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2019-03-25 03:21 |
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Revised |
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2019-04-23 15:36 |
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Second Decision |
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2019-04-26 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-04-28 00:09 |
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Articles in Press |
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2019-04-28 00:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-05-25 07:10 |
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Publish the Manuscript Online |
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2019-05-27 08:24 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Carvedilol vs endoscopic variceal ligation for primary and secondary prevention of variceal bleeding: Systematic review and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Michael Dwinata, David Dwi Putera, Muhamad Fajri Adda'i, Putra Nur Hidayat and Irsan Hasan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Michael Dwinata, MD, Staff Physician, Department of Internal Medicine, Depati Hamzah General Hospital, Soekarno Hatta Street, Girimaya, Pangkalpinang 33684, Indonesia. mdwinata@gmail.com |
| Key Words |
Carvedilol; Liver cirrhosis; Variceal hemorrhage; Portal hypertension; Prophylaxis |
| Core Tip |
This study was an updated meta-analysis of primary prevention and the first meta-analysis of secondary prevention of variceal bleeding in cirrhotic patients. Seven relevant randomized controlled trials were included. Based on the pooled analysis, carvedilol had similar efficacy to endoscopic variceal ligation (EVL) in preventing the first variceal hemorrhage in cirrhosis patients with esophageal varices. Carvedilol was superior to EVL for secondary prevention of variceal bleeding in regard to all-cause mortality reduction by 49% (RR: 0.51, 95%CI: 0.33–0.79). |
| Publish Date |
2019-05-27 08:24 |
| Citation |
Dwinata M, Putera DD, Adda’i MF, Hidayat PN, Hasan I. Carvedilol vs endoscopic variceal ligation for primary and secondary prevention of variceal bleeding: Systematic review and meta-analysis. World J Hepatol 2019; 11(5): 464-476 |
| URL |
https://www.wjgnet.com/1948-5182/full/v11/i5/464.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v11.i5.464 |
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