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10/16/2019 12:17:24 PM | Browse: 1262 | Download: 2365
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 46481
Country United States
Received
2019-02-26 06:58
Peer-Review Started
2019-02-27 12:53
First Decision by Editorial Office Director
2019-07-31 03:37
Return for Revision
2019-08-21 03:34
Revised
2019-09-03 04:17
Publication Fee Transferred
Second Decision by Editor
2019-09-12 09:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2019-09-12 16:39
Articles in Press
2019-09-12 16:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-23 06:26
Publish the Manuscript Online
2019-10-16 12:17
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Evaluation of the safety and effectiveness of direct oral anticoagulants and low molecular weight heparin in gastrointestinal cancer-associated venous thromboembolism
Manuscript Source Unsolicited Manuscript
All Author List Alejandro Recio-Boiles, Sumana Veeravelli, Jessica Vondrak, Hani M Babiker, Aaron J Scott, Rachna T Shroff, Hitendra Patel, Emad Elquza and Ali McBride
ORCID
Author(s) ORCID Number
Alejandro Recio-Boiles http://orcid.org/0000-0002-5423-3112
Sumana Veeravelli http://orcid.org/0000-0002-7179-6996
Jessica Vondrak http://orcid.org/0000-0001-7570-8538
Hani M Babiker http://orcid.org/0000-0002-9368-6296
Aaron J Scott http://orcid.org/0000-0002-0301-3072
Rachna T Shroff http://orcid.org/0000-0003-0066-2672
Hitendra Patel http://orcid.org/0000-0001-8746-2600
Emad Elquza http://orcid.org/0000-0003-3383-7950
Ali McBride http://orcid.org/0000-0002-9430-4675
Funding Agency and Grant Number
Corresponding Author Alejandro Recio-Boiles, MD, Academic Fellow, Department of Medicine, Hematology and Medical Oncology, University of Arizona Cancer Center, 1515 N Campbell Ave, Tucson, AZ 85724, United States. areciomd@email.arizona.edu
Key Words Direct oral anticoagulants; Low molecular weight heparin; Gastrointestinal cancer; Venous thromboembolism; Cancer associated thrombosis; Clinical risk
Core Tip Our study shows similar efficacy of low molecular weight heparin as compared to apixaban and rivaroxaban. However, side effect profiles of these new direct oral anticoagulants (DOAC)’s may lead to a preferred use of apixaban, which had lower bleeding events in the highly sensitive gastrointestinal cancer (GICA) patient population. GICA-venous thromboembolism (VTE) is a high-risk patient subpopulation and warrants additional dedicated prospective clinical analysis of the efficacy and safety of DOACs. In addition, evaluation of clinical predictors that may influence the risk of VTE recurrence and major bleeding should include GICA as a high-risk group.
Publish Date 2019-10-16 12:17
Citation Recio-Boiles A, Veeravelli S, Vondrak J, Babiker HM, Scott AJ, Shroff RT, Patel H, Elquza E, Ali McBride A. Evaluation of the safety and effectiveness of direct oral anticoagulants and low molecular weight heparin in gastrointestinal cancer-associated venous thromboembolism. World J Gastrointest Oncol 2019; 11(10): 866-876
URL https://www.wjgnet.com/1948-5204/full/v11/i10/866.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i10.866
Full Article (PDF) WJGO-11-866.pdf
Full Article (Word) WJGO-11-866.docx