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Articles Published Processes
5/20/2019 9:05:35 AM | Browse: 953 | Download: 2208
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Received |
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2019-02-14 07:59 |
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Peer-Review Started |
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2019-02-17 09:33 |
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To Make the First Decision |
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2019-03-20 06:45 |
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Return for Revision |
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2019-03-21 07:22 |
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Revised |
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2019-03-29 05:26 |
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Second Decision |
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2019-04-19 07:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-04-20 02:02 |
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Articles in Press |
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2019-04-20 02:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-24 13:16 |
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Typeset the Manuscript |
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2019-05-20 00:46 |
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Publish the Manuscript Online |
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2019-05-20 09:05 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Risk factors for progression to acute-on-chronic liver failure during severe acute exacerbation of chronic hepatitis B virus infection
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ling Yuan, Bai-Mei Zeng, Lu-Lu Liu, Yi Ren, Yan-Qing Yang, Jun Chu, Ying Li, Fang-Wan Yang, Yi-Huai He and Shi-De Lin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Funds of Chinese National Natural Science Foundation Project |
81460124 |
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| Corresponding Author |
Shi-De Lin, MD, Chief Doctor, Occupational Physician, Professor, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, 201 Dalian street, Zunyi 563003, Guizhou Province, China. linshide6@zmc.edu.cn |
| Key Words |
Acute-on-chronic liver failure; Chronic hepatitis B; Hepatic decompensation; Liver cirrhosis; Risk factors; Severe acute exacerbation |
| Core Tip |
The risk factors related to progression in patients with severe acute exacerbation (SAE) of chronic hepatitis B virus (HBV) infection remain unknown. This is the largest study to identify the risk factors related to progression to hepatic decompensation (HD) and acute-on-chronic liver failure (ACLF) in compensated patients with SAE of chronic HBV infection. We found liver cirrhosis is an independent risk factor for progression to both HD and ACLF. High model for end-stage liver disease score, high aspartate aminotransferase, and low prothrombin activity are associated with progression to ACLF. |
| Publish Date |
2019-05-20 09:05 |
| Citation |
Yuan L, Zeng BM, Liu LL, Ren Y, Yang YQ, Chu J, Li Y, Yang FW, He YH, Lin SD. Risk factors for progression to acute-on-chronic liver failure during severe acute exacerbation of chronic hepatitis B virus infection. World J Gastroenterol 2019; 2019; 25(19): 2327-2337 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i19/2327.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i19.2327 |
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