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Articles Published Processes
3/31/2019 7:22:50 AM | Browse: 969 | Download: 1435
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Received |
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2019-02-20 07:42 |
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Peer-Review Started |
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2019-02-20 09:19 |
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To Make the First Decision |
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2019-03-07 05:59 |
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Return for Revision |
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2019-03-07 06:24 |
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Revised |
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2019-03-12 08:21 |
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Second Decision |
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2019-03-15 09:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-16 22:34 |
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Articles in Press |
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2019-03-16 22:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-03-29 03:11 |
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Publish the Manuscript Online |
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2019-03-31 07:22 |
ISSN |
2308-3840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Review |
Article Title |
Prospects for immunotherapy as a novel therapeutic strategy against hepatocellular carcinoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Yu Akazawa, Toshihiro Suzuki, Toshiaki Yoshikawa, Shoichi Mizuno, Yasunari Nakamoto and Tetsuya Nakatsura |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Tetsuya Nakatsura, MD, PhD, Doctor, Doctor, Professor, Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan. tnakatsu@east.ncc.go.jp |
Key Words |
Hepatocellular carcinoma; Cancer immunotherapy; Immune checkpoint inhibitor; Glypican-3; Cancer vaccine; Clinical trials; Cytotoxic T-lymphocytes |
Core Tip |
Hepatocellular carcinoma (HCC) is a highly aggressive malignant disease, with a poor prognosis. Recent developments and advances in cancer immunotherapy, particularly immune checkpoint inhibitor therapy, could lead to a major paradigm shift in standard HCC therapy. This review aims to provide an overview of novel immunotherapies, including antigen-based immunotherapies such as glypican-3-targeted immunotherapy, and immune checkpoint inhibitor therapy against HCC. It also discusses the future prospects of cancer immunotherapy against HCC. |
Publish Date |
2019-03-31 07:22 |
Citation |
Akazawa Y, Suzuki T, Yoshikawa T, Mizuno S, Nakamoto Y, Nakatsura T. Prospects for immunotherapy as a novel therapeutic strategy against hepatocellular carcinoma. World J Meta-Anal 2019; 7(3): 80-95 |
URL |
https://www.wjgnet.com/2308-3840/full/v7/i3/80.htm |
DOI |
https://dx.doi.org/10.13105/wjma.v7.i3.80 |
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