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Articles Published Processes
8/26/2019 10:16:55 AM | Browse: 1191 | Download: 1147
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Received |
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2019-02-26 02:01 |
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Peer-Review Started |
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2019-02-27 11:23 |
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To Make the First Decision |
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2019-06-05 06:24 |
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Return for Revision |
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2019-06-27 01:36 |
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Revised |
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2019-07-04 13:15 |
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Second Decision |
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2019-07-12 11:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-07-16 22:31 |
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Articles in Press |
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2019-07-16 22:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-22 12:07 |
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Publish the Manuscript Online |
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2019-08-26 10:16 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Opinion Review |
| Article Title |
Neural regeneration by regionally induced stem cells within post-stroke brains: Novel therapy perspectives for stroke patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Takayuki Nakagomi, Toshinori Takagi, Mikiya Beppu, Shinichi Yoshimura and Tomohiro Matsuyama |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Japan Society for the Promotion of Science (JSPS) KAKENHI |
No. 15K06723 |
| Japan Society for the Promotion of Science (JSPS) KAKENHI |
No. 18K07380 |
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| Corresponding Author |
Takayuki Nakagomi, MD, PhD, Professor, Institute for Advanced Medical Sciences, Department of therapeutic progress in brain diseases, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya 663-8501, Hyogo, Japan. nakagomi@hyo-med.ac.jp |
| Key Words |
Ischemic stroke; Stroke patients; Central nervous system; Neural stem/progenitor cells; Multipotent stem cells; Stem-cell-based therapies |
| Core Tip |
Ischemic stroke is a critical disease that is accompanied by serious symptoms, such as paresis. Until recently, it was believed that areas affected by stroke mainly consist of necrotic and inflammatory cells. However, we have recently demonstrated that novel ischemia-induced stem cells can be isolated from not only mouse brains after stroke but also human brains after stroke. These stem cells exhibited the multipotency and differentiated into electrophysiologically functional neurons. In this article, we introduce the future perspectives for patients suffering from ischemic stroke using these regionally derived stem cells. |
| Publish Date |
2019-08-26 10:16 |
| Citation |
Nakagomi T, Takagi T, Beppu M, Yoshimura S, Matsuyama T. Neural regeneration by regionally induced stem cells within post-stroke brains: Novel therapy perspectives for stroke patients. World J Stem Cells 2019; 11(8):452-463 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i8/452.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i8.452 |
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