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8/26/2019 10:16:55 AM | Browse: 622 | Download: 73
Publication Name World Journal of Stem Cells
Manuscript ID 46614
Country/Territory Japan
2019-02-26 02:01
Peer-Review Started
2019-02-27 11:23
To Make the First Decision
2019-06-05 06:24
Return for Revision
2019-06-27 01:36
2019-07-04 13:15
Second Decision
2019-07-12 11:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-16 22:31
Articles in Press
2019-07-16 22:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-08-22 12:07
Publish the Manuscript Online
2019-08-26 10:16
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Opinion Review
Article Title Neural regeneration by regionally induced stem cells within post-stroke brains: Novel therapy perspectives for stroke patients
Manuscript Source Invited Manuscript
All Author List Takayuki Nakagomi, Toshinori Takagi, Mikiya Beppu, Shinichi Yoshimura and Tomohiro Matsuyama
Author(s) ORCID Number
Takayuki Nakagomi http://orcid.org/0000-0003-2274-410X
Toshinori Takagi http://orcid.org/0000-0002-6375-9941
Mikiya Beppu http://orcid.org/0000-0003-3484-5733
Shinichi Yoshimura http://orcid.org/0000-0002-3600-4842
Tomohiro Matsuyama http://orcid.org/0000-0002-2177-1862
Funding Agency and Grant Number
Funding Agency Grant Number
Japan Society for the Promotion of Science (JSPS) KAKENHI No. 15K06723
Japan Society for the Promotion of Science (JSPS) KAKENHI No. 18K07380
Corresponding author Takayuki Nakagomi, MD, PhD, Professor, Institute for Advanced Medical Sciences, Department of therapeutic progress in brain diseases, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya 663-8501, Hyogo, Japan. nakagomi@hyo-med.ac.jp
Keywords Ischemic stroke; Stroke patients; Central nervous system; Neural stem/progenitor cells; Multipotent stem cells; Stem-cell-based therapies
Core Tip Ischemic stroke is a critical disease that is accompanied by serious symptoms, such as paresis. Until recently, it was believed that areas affected by stroke mainly consist of necrotic and inflammatory cells. However, we have recently demonstrated that novel ischemia-induced stem cells can be isolated from not only mouse brains after stroke but also human brains after stroke. These stem cells exhibited the multipotency and differentiated into electrophysiologically functional neurons. In this article, we introduce the future perspectives for patients suffering from ischemic stroke using these regionally derived stem cells.
Publish Date 2019-08-26 10:16
Citation Nakagomi T, Takagi T, Beppu M, Yoshimura S, Matsuyama T. Neural regeneration by regionally induced stem cells within post-stroke brains: Novel therapy perspectives for stroke patients. World J Stem Cells 2019; 11(8):452-463
Url https://www.wjgnet.com/1948-0210/full/v11/i8/452.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i8.452
Full Article (PDF) WJSC-11-452.pdf
Full Article (Word) WJSC-11-452.docx
Manuscript File 46614-Review.docx
Answering Reviewers 46614-Answering reviewers.pdf
Audio Core Tip 46614-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 46614-Conflict-of-interest statement.pdf
Copyright License Agreement 46614-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46614-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 46614-Language certificate.pdf
Peer-review Report 46614-Peer-review(s).pdf
Scientific Misconduct Check 46614-Scientific misconduct check.pdf
Scientific Editor Work List 46614-Scientific editor work list.pdf