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Articles Published Processes
7/6/2019 6:23:58 AM | Browse: 888 | Download: 1736
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Received |
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2019-02-21 01:55 |
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Peer-Review Started |
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2019-02-22 02:52 |
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To Make the First Decision |
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2019-04-30 10:09 |
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Return for Revision |
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2019-05-05 01:19 |
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Revised |
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2019-05-14 16:49 |
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Second Decision |
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2019-05-30 08:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-06-01 13:25 |
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Articles in Press |
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2019-06-01 13:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-07-04 07:15 |
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Publish the Manuscript Online |
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2019-07-06 06:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Fate plasticity in the intestine: The devil is in the detail
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Simon Buczacki |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Cancer Research UK |
C14094/A27178 |
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| Corresponding Author |
Simon Buczacki, FRCS, MBChB, PhD, Senior Scientist, Surgical Oncologist, Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Addenbrooke’s Biomedical Campus, Robinson Way, Cambridge CB2 0AF, United Kingdom. sjab2@cam.ac.uk |
| Key Words |
Intestinal stem cell; Plasticity; Lgr5; Regeneration |
| Core Tip |
Recent advances, using transgenic mice, in understanding cellular hierarchies in the intestinal epithelium have identified numerous cell populations which retain the ability to change their fate in response to injury. Here, these new studies are presented in the context of a discussion about what represents a relevant epithelial injury to understand ‘homeostatic regeneration’. Experimental suggestions are proposed for validating animal findings to translate our current knowledge to better understand human intestinal epithelial maintenance. |
| Publish Date |
2019-07-06 06:23 |
| Citation |
Buczacki S. Fate plasticity in the intestine: The devil is in the detail. World J Gastroenterol 2019; 25(25): 3116-3122 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i25/3116.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i25.3116 |
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