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Articles Published Processes
6/26/2019 11:43:52 AM | Browse: 980 | Download: 1495
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Received |
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2019-02-23 06:10 |
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Peer-Review Started |
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2019-02-26 00:25 |
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To Make the First Decision |
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2019-03-18 06:29 |
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Return for Revision |
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2019-03-22 01:30 |
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Revised |
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2019-04-03 11:01 |
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Second Decision |
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2019-04-30 08:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-06 02:04 |
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Articles in Press |
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2019-05-06 02:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-06-24 10:27 |
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Publish the Manuscript Online |
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2019-06-26 11:43 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Effect of aging on behaviour of mesenchymal stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Juan Fafián-Labora, Miriam Morente-López and María C Arufe |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Xunta de Galicia |
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| Corresponding Author |
María C Arufe, PhD, Professor, Grupo de Terapia Celular y Medicina Regenerativa, Departamento de Fisioterapia, Ciencias Biomédicas y Medicina, Universidade da Coruña, Facultad de Ciencias de la Salud, Campus de Oza, INIBIC-CHUAC, A Coruña 15006, Spain. maria.arufe@udc.es |
| Key Words |
Mesenchymal stem cells; Aging; Autophagy; Mitochondrial stress; Extracellular vesicles |
| Core Tip |
The point of interest of this work is the behaviour of the mesenchymal stromal cell (MSC) through aging, which can occur over time in the culture (in vitro) or in its own physiological niche (in vivo). This review defines the current knowledge published in the MSC field that focuses mainly on the mechanisms that influence its senescence in vivo and in vitro in the last three years. Three cellular mechanisms are of special importance in this review, since they can decisively influence the behaviour of MSC in aging, such as autophagy, oxidative stress and the production of extracellular vesicles. |
| Publish Date |
2019-06-26 11:43 |
| Citation |
Fafián-Labora JA, Morente-López M, Arufe MC. Effect of aging on behaviour of mesenchymal stem cells. World J Stem Cells 2019; 11(6): 337-346 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i6/337.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i6.337 |
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