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Articles Published Processes
9/25/2019 3:03:24 AM | Browse: 827 | Download: 1130
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Received |
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2019-02-28 01:43 |
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Peer-Review Started |
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2019-03-04 08:29 |
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To Make the First Decision |
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2019-08-06 02:56 |
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Return for Revision |
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2019-08-08 01:09 |
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Revised |
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2019-08-15 18:06 |
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Second Decision |
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2019-08-29 04:16 |
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Accepted by Journal Editor-in-Chief |
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2019-08-30 19:15 |
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Accepted by Executive Editor-in-Chief |
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2019-09-05 02:49 |
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Articles in Press |
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2019-09-05 02:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-12 07:21 |
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Publish the Manuscript Online |
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2019-09-25 03:03 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Tendon stem/progenitor cell ageing: Modulation and rejuvenation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Guang-Chun Dai, Ying-Juan Li, Min-Hao Chen, Pan-Pan Lu and Yun-Feng Rui |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81871812, 81572187 |
| National Natural Science Foundation of China for Young Scholars |
81201422 |
| Natural Science Foundation of Jiangsu Province for Young Scholars |
BK2012334 |
| Summit of the Six Top Talents” Program of Jiangsu Province |
2013-WSW-054 |
| Jiangsu Provincial Medical Talent, The Project of Invigorating Health Care through Science, Technology and Education |
ZDRCA2016083 |
| The Six Projects Sponsoring Talent Summits of Jiangsu Province, China |
LGY2017099 |
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| Corresponding Author |
Yun-Feng Rui, MD, PhD, Associate Professor, Chief Doctor, Department of Orthopaedics, Zhongda Hospital, School of Medicine, Southeast University, NO.87 Ding Jia Qiao, Nanjing 210009, Jiangsu Province, China. ruiyunfeng@126.com |
| Key Words |
Tendon Stem/Progenitor Cell; Ageing; Mechanisms; Modulation; Rejuvenation; |
| Core Tip |
Tendon stem/progenitor cells (TSPCs) play an essential role in tendon maintenance, regeneration and repair. Recent studies indicate that an association between the decreased capacities of aged TSPCs and the impaired tendon functions observed with increasing age. In this review, we briefly discuss novel updates in research investigating TSPCs characteristics. Then, we summarize the epigenetic variations in TSPCs that occur with ageing and provide a detailed description of the pathways that play essential roles in the cellular ageing process. Finally, we propose potential methods to rejuvenate ageing TSPCs and provide additional therapeutic targets for the treatment of age-related tendon diseases. |
| Publish Date |
2019-09-25 03:03 |
| Citation |
Dai GC, Li YJ, Chen MH, Lu PP, Rui YF. Tendon stem/progenitor cell ageing: Modulation and rejuvenation. World J Stem Cells 2019; 11(9):677-692 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i9/677.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i9.677 |
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