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3/31/2019 7:22:50 AM | Browse: 910 | Download: 1095
Publication Name World Journal of Meta-Analysis
Manuscript ID 46777
Country United States
Received
2019-02-22 00:40
Peer-Review Started
2019-02-22 06:58
To Make the First Decision
2019-03-05 11:50
Return for Revision
2019-03-07 06:20
Revised
2019-03-21 07:56
Second Decision
2019-03-25 01:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-25 05:29
Articles in Press
2019-03-25 05:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-03-29 03:13
Publish the Manuscript Online
2019-03-31 07:22
ISSN 2308-3840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Meta-Analysis
Article Title Higher dose of simethicone decreases colonic bubbles and increases prep tolerance and quality of bowel prep: Meta-analysis of randomized controlled trials
Manuscript Source Invited Manuscript
All Author List Mohammad F Madhoun, Maham Hayat and Ijlal Akbar Ali
ORCID
Author(s) ORCID Number
Mohammad F Madhoun http://orcid.org/0000-0001-9267-3023
Maham Hayat http://orcid.org/https://orcid.org/0000-0001-5332-0823
Ijlal Akbar Ali http://orcid.org/https://orcid.org/0000-0002-9173-7053
Funding Agency and Grant Number
Corresponding Author Mohammad F Madhoun, MD, MSc, Academic Fellow, Associate Professor, Doctor, Division of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Andrews Academic Tower, Suite 7426, 800 Stanton L. Young Blvd, Oklahoma, OK 73104, United States. mohammad-madhoun@ouhsc.edu
Key Words Simethicone; Colonoscopy; Bubbles; Bowel preparation; Adenoma detection rate
Core Tip Colonoscopy is an essential tool in the screening for and preventing colon cancer, but inadequate colon preparation limits visualization, prolongs procedure time, and, affects exam quality. An antifoaming agent, simethicone, has been a promising addition to bowel preparation. This meta-analysis of randomized controlled trials assessed the effect of its addition to commonly utilized bowel preparations and analyzed the optimum effective dose. We concluded that the addition of simethicone to bowel preparation significantly reduced inadequate bowel preparation, increased adenoma detection rate and trended to improved tolerability of the prep. Higher doses of simethicone were more likely to achieve those outcomes.
Publish Date 2019-03-31 07:22
Citation Madhoun MF, Hayat M, Ali IA. Higher dose of simethicone decreases colonic bubbles and increases prep tolerance and quality of bowel prep: Meta-analysis of randomized controlled trials. World J Meta-Anal 2019; 7(3): 110-119
URL https://www.wjgnet.com/2308-3840/full/v7/i3/110.htm
DOI https://dx.doi.org/10.13105/wjma.v7.i3.110
Full Article (PDF) WJMA-7-110.pdf
Full Article (Word) WJMA-7-110.docx
PRISMA 2009 Checklist 46777-PRISMA-2009-Checklist-revision.pdf
Manuscript File 46777-Review.docx
Answering Reviewers 46777-Answering reviewers.pdf
Audio Core Tip 46777-Audio core tip.wav
Biostatistics Review Certificate 46777-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 46777-Conflict-of-interest statement.pdf
Copyright License Agreement 46777-Copyright license agreement.pdf
Supplementary Material 46777-Supplementary material.pdf
Peer-review Report 46777-Peer-review(s).pdf
Scientific Misconduct Check 46777-Scientific misconduct check.pdf
Scientific Editor Work List 46777-Scientific editor work list.pdf