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Articles Published Processes
6/12/2019 3:49:25 AM | Browse: 731 | Download: 888
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Received |
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2019-02-28 01:35 |
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Peer-Review Started |
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2019-03-04 10:55 |
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To Make the First Decision |
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2019-04-12 00:50 |
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Return for Revision |
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2019-04-19 10:14 |
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Revised |
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2019-04-19 18:31 |
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Second Decision |
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2019-04-30 09:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-05-05 23:56 |
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Articles in Press |
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2019-05-05 23:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-05-16 06:51 |
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Publish the Manuscript Online |
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2019-06-12 03:49 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Current controversies and future perspectives on treatment of intensive care unit delirium in adults
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Cascella, Marco Fiore, Sebastiano Leone, Domenico Carbone and Raffaela Di Napoli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Cascella, MD, Academic Fellow, Professor, Division of Anesthesia and Pain Management, Istituto Nazionale Tumori, IRCSS Fondazione G. Pascale, Via Mariano Semmola, 53, Naples 80049, Italia, Italy. m.cascella@istitutotumori.na.it |
| Key Words |
Delirium; Intensive care; Haloperidol; Antipsychotic agents; Major tranquilizers; Cognitive decline; Dexmedetomidine |
| Core Tip |
Delirium represents the most common type of acute brain dysfunction in intensive care unit (ICU). Despite no support from rigorous controlled studies, haloperidol and atypical antipsychotics have been for decades the main class of drugs used for its pharmacological management. Recently, large size studies demonstrated that antipsychotics do not significantly shorten the duration of delirium. However, because ICU delirium has multifactorial pathogenesis it is difficult to postulate that a single agent can be useful for all clinical contexts. In this manuscript we want to provide an overview of most recent pharmacological approaches for the ICU delirium treatment. |
| Publish Date |
2019-06-12 03:49 |
| Citation |
Cascella M, Fiore M, Leone S, Carbone D, Di Napoli R. Current controversies and future perspectives on treatment of intensive care unit delirium in adults. World J Crit Care Med 2019; 8(3): 18-27 |
| URL |
https://www.wjgnet.com/2220-3141/full/v8/i3/18.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v8.i3.18 |
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