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Articles Published Processes
6/6/2019 8:31:40 AM | Browse: 773 | Download: 1647
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Received |
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2019-03-02 05:44 |
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Peer-Review Started |
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2019-03-03 09:14 |
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To Make the First Decision |
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2019-03-20 06:47 |
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Return for Revision |
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2019-03-21 07:42 |
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Revised |
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2019-03-27 05:42 |
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Second Decision |
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2019-04-19 07:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-04-20 01:57 |
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Articles in Press |
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2019-04-20 01:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-24 13:16 |
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Typeset the Manuscript |
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2019-06-03 05:55 |
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Publish the Manuscript Online |
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2019-06-06 08:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Systems pharmacology approach reveals protective mechanisms of Jian-Pi Qing-Chang decoction on ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
You-Lan Chen, Yi-Yuan Zheng, Yan-Cheng Dai, Ya-Li Zhang and Zhi-Peng Tang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Funds of China |
81573892 |
| National Natural Science Funds of China |
81873253 |
| National Natural Science Funds of China |
81704009 |
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| Corresponding Author |
Zhi-Peng Tang, MD, PhD, Director, Doctor, Professor, Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Shanghai 200032, China. zhipengtang@sohu.com |
| Key Words |
Systems pharmacology; Ulcerative colitis; Jian-Pi Qing-Chang decoction; Inflammation; Intestinal epithelial barrier function |
| Core Tip |
Given the complex pathogenesis of ulcerative colitis (UC), the conventional therapeutic methods are not fully curative. As a sort of systematic complementary and alternative medicine, traditional Chinese medicine (TCM) provides new options for the standard therapy. Nevertheless, there are still numerous problems with the promotion of TCM attributed to its complexity, and consequently, new research approaches are urgently needed. Thus, we explored the protective effects of Jian-Pi Qing-Chang decoction on UC based on systems pharmacology approach, which might fill the current innovation gap in drug discovery and clinical practice pertaining to TCM. |
| Publish Date |
2019-06-06 08:31 |
| Citation |
Chen YL, Zheng YY, Dai YC, Zhang YL, Tang ZP. Systems pharmacology approach reveals protective mechanisms of Jian-Pi Qing-Chang decoction on ulcerative colitis. World J Gastroenterol 2019; 25(21): 2603-2622 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i21/2603.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i21.2603 |
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