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Articles Published Processes
6/6/2019 8:31:40 AM | Browse: 1100 | Download: 1596
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Received |
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2019-03-12 08:16 |
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Peer-Review Started |
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2019-03-13 00:49 |
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To Make the First Decision |
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2019-04-11 08:18 |
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Return for Revision |
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2019-04-12 01:40 |
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Revised |
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2019-04-21 05:22 |
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Second Decision |
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2019-04-30 09:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-03 12:01 |
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Articles in Press |
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2019-05-03 12:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-08 02:29 |
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Typeset the Manuscript |
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2019-06-03 05:54 |
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Publish the Manuscript Online |
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2019-06-06 08:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Association of proton pump inhibitors with the risk of hepatic encephalopathy in advanced liver disease: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xin-Xing Tantai, Long-Bao Yang, Zhong-Cao Wei, Cai-Lan Xiao, Li-Rong Chen, Jin-Hai Wang and Na Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Na Liu, PhD, Doctor, Doctor, Division of Gastroenterology, The Second Affiliated Hospital, Xi’an Jiaotong University, No. 157, Xi Wu Road, Xi’an 710004, Shaanxi Province, China. liunafmmu@163.com |
| Key Words |
Proton pump inhibitors; Cirrhosis; Hepatic encephalopathy; Systematic review; Meta-analysis |
| Core Tip |
Proton pump inhibitors (PPIs) are very commonly used in patients with advanced liver disease. Remarkably, previous studies have shown that approximately 50% of indications for PPIs treatment were unclear or inadequate in this special group of patients. All this may be because PPIs are generally considered safe. However, this meta-analysis shows that using PPIs is associated with an increased risk of hepatic encephalopathy (HE) in patients with advanced liver disease. This reminds clinicians that inappropriate use of PPIs may be not beneficial but put patients at an elevated risk of HE. These findings still need to be confirmed by more high-quality prospective studies because of the limitations of this meta-analysis. |
| Publish Date |
2019-06-06 08:31 |
| Citation |
Tantai XX, Yang LB, Wei ZC, Xiao CL, Chen LR, Wang JH, Liu N. Association of proton pump inhibitors with the risk of hepatic encephalopathy in advanced liver disease: A meta-analysis. World J Gastroenterol 2019; 25(21): 2683-2698 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i21/2683.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i21.2683 |
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