Publication Name	World Journal of Gastroenterology
Manuscript ID	4704
Country	China

Received	2013-07-17 10:34
Peer-Review Started	2013-07-17 15:14
To Make the First Decision	2013-09-02 16:28
Return for Revision	2013-09-03 21:27
Revised
Second Decision	2013-10-21 17:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-22 07:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-01 18:14
Publish the Manuscript Online	2013-12-18 10:00

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Autobiography
Article Title	Association between TNF-α and IL-1β genotypes vs Helicobacter pylori infection in Indonesia
Manuscript Source	Invited Manuscript
All Author List	Yang Zhao, Jing-Wen Wang, Tsutomu Tanaka, Akihiro Hosono, Ryosuke Ando, Shinkan Tokudome, Soeripto, FX Ediati Triningsih, Tegu Triono, Suwignyo Sumoharjo, EY Wenny Astuti Achwan, Stephanus Gunawan and Yu-Min Li
Funding Agency and Grant Number
Corresponding Author	Yu-Min Li, PhD, Professor, First Department of General Surgery, Second Hospital of Lanzhou University, 82 Cuiyingmen, Lanzhou 730030, Gansu Province, China. liym@lzu.edu.cn
Key Words	Helicobacter pylori; Tumor necrosis factor; Interleukin-1β; Infection; Allele
Core Tip	We found single nucleotide polymorphism of tumor necrosis factor-α and allele of interleukin-1β having high frequency in the healthy Indonesian population, which may be associated with potential contact with Helicobacter pylori (H. pylori) infection. Throughout, H. pylori studies were conducted in patients, and treatment was based on quadruple antibiotics to eradicate H. pylori infection in clinical trials. However, the implications of the individual differences in recurrent infections and drug resistance of H. pylori and other issues must be addressed. Therefore, vaccine development for prevention of H. pylori will be a topical issue in the coming years.
Publish Date	2013-12-18 10:00
Citation	Zhao Y, Wang JW, Tanaka T, Hosono A, Ando R, Tokudome S, Soeripto, Triningsih FXE, Triono T, Sumoharjo S, Achwan EYWA, Gunawan S, Li YM. Association between TNF-α and IL-1β genotypes vs Helicobacter pylori infection in Indonesia. World J Gastroenterol 2013; 19(46): 8758-8763
URL	http://www.wjgnet.com/1007-9327/full/v19/i46/8758.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i46.8758

Full Article (PDF)	WJG-19-8758.pdf
Manuscript File	4704-Review.doc
Answering Reviewers	4704-Answering reviewers.pdf
Copyright License Agreement	4704-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20130717084123.pdf
Non-Native Speakers of English Editing Certificate	4704-Language certificate.pdf
Peer-review Report	4704-Peer review(s).pdf
Scientific Editor Work List	4704-Scientific editor work list.doc