ISSN |
1948-5190 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects
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Manuscript Source |
Invited Manuscript |
All Author List |
Diogo Turiani Hourneaux de Moura, Bruna Furia Buzetti Hourneaux de Moura, Michael A Manfredi, Kelly E Hathorn, Ahmad N Bazarbashi, Igor Braga Ribeiro, Eduardo Guimarães Hourneaux de Moura and Christopher C Thompson |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Igor Braga Ribeiro, MD, Academic Fellow, Research Fellow, Surgeon, Department of Endoscopy of Clinics Hospital of São Paulo University, Av. Dr. Enéas de Carvalho Aguiar 255, Instituto Central, Prédio dos Ambulatórios, Pinheiros, São Paulo 05403-000, Brazil. igorbraga1@gmail.com |
Key Words |
Gastrointestinal; Endoscopy; Endoscopic vacuum therapy; Negative pressure therapy; Fistula; Leak; Perforation; Defect |
Core Tip |
Gastrointestinal (GI) transmural defects, including perforations, leaks, and fistulas, are difficult to manage and are associated with high rates of morbidity and mortality. Endoscopic vacuum therapy (EVT) has developed into a valuable tool for the treatment of these conditions. EVT has proven to be an effective and safe method in the intraluminal treatment of transmural defects, as it promotes changes in perfusion, causes microdeformation and macrodeformation, and decreases bacterial contamination, secretion, and local edema to facilitate healing. In this review, we discuss the mechanism of action, materials, techniques, efficacy, and safety of EVT in the management of patients with transmural GI defects. |
Publish Date |
2019-05-16 14:12 |
Citation |
de Moura DTH, de Moura BFBH, Manfredi MA, Harthon KE, Bazerbashi AN, Ribeiro IB, de Moura EGH, Thompson CC. Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects. World J Gastrointest Endosc 2019; 11(5): 329-344 |
URL |
URL: https://www.wjgnet.com/1948-5190/full/v11/i5/329.htm |
DOI |
DOI: https://dx.doi.org/10.4253/wjge.v11.i5.329 |