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Articles Published Processes
12/30/2019 1:55:29 AM | Browse: 813 | Download: 1389
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Received |
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2019-03-07 01:36 |
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Peer-Review Started |
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2019-03-08 03:41 |
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To Make the First Decision |
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2019-04-16 07:41 |
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Return for Revision |
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2019-05-10 00:18 |
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Revised |
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2019-05-13 08:22 |
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Second Decision |
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2019-09-06 10:03 |
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Accepted by Journal Editor-in-Chief |
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2019-09-06 21:02 |
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Accepted by Executive Editor-in-Chief |
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2019-12-02 19:54 |
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Articles in Press |
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2019-12-02 19:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-12-09 06:54 |
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Publish the Manuscript Online |
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2019-12-30 01:55 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Early therapeutic effect of platelet rich fibrin combined with allogenic bone marrow-derived stem cells on rats' critical sized mandibular defects
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammad A Awadeen, Fouad A Al-Belasy, Laila E Amin, Mohamad E Helal and Mohammed E Grawish |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed E Grawish, MSc, PhD, Professor, Department of Oral Biology, Faculty of Dentistry, Mansoura University, Dakahlia Governorate, Mansoura 740005, Egypt. grawish2005@yahoo.com |
| Key Words |
Platelet rich fibrin membrane; Bone marrow-derived stem cells; Critical-sized mandibular defects; Rats; Histological and immunohistochemical staining; |
| Core Tip |
Our findings derived from rat models for treating the critical sized mandibular bone defects with platelet rich fibrin (PRF) membranes seeded with allogeneic bone marrow-derived stem cells (BMSCs) confirmed the in-vivo anti-inflammatory effects of allogenic BMSCs and indicated that they have beneficial syngeneic effects to the PRF membranes in promoting and accelerating the healing of critically sized mandibular defects. The routine and special histological and immunohistochemical staining demonstrates for the first time that experimentally treated critically sized mandibular defects with the combination therapy of PRF membranes and BMSCs increased the amount and the rate of the newly formed bone and decreased the amount of granulation tissue with the reduction in the number of the inflammatory cell infiltrates. |
| Publish Date |
2019-12-30 01:55 |
| Citation |
Awadeen MA, Al-Belasy FA, Ameen LE, Helal ME, Grawish ME. Early therapeutic effect of platelet rich fibrin combined with allogenic bone marrow-derived stem cells on rats' critical sized mandibular defects. World J Stem Cells 2020; 12(1): 55-69 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i1/55.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i1.55 |
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