Publication Name	World Journal of Gastroenterology
Manuscript ID	47389
Country	Italy

Received	2019-03-14 03:47
Peer-Review Started	2019-03-14 06:31
To Make the First Decision	2019-04-11 08:21
Return for Revision	2019-04-12 02:57
Revised	2019-04-30 11:18
Second Decision	2019-05-08 08:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-05-08 16:08
Articles in Press	2019-05-08 16:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-06-13 08:26
Publish the Manuscript Online	2019-06-14 09:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Autoimmune hepatitis treatment in the elderly: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Marilena Durazzo, Giulia Lupi, Michela Scandella, Arianna Ferro and Gabriella Gruden
ORCID	Author(s) ORCID Number Marilena Durazzo http://orcid.org/0000-0003-2450-5911 Giulia Lupi http://orcid.org/0000-0001-6198-4013 Michela Scandella http://orcid.org/0000-0002-4734-9547 Arianna Ferro http://orcid.org/0000-0002-1450-7035 Gabriella Gruden http://orcid.org/0000-0001-8906-9589
Funding Agency and Grant Number
Corresponding Author	Marilena Durazzo, MD, PhD, Associate Professor, Department of Medical Sciences, University of Turin, C So AM Dogliotti 14, Turin 10126, Italy. marilena.durazzo@unito.it
Key Words	Autoimmune hepatitis; Elderly patients; Aged; Steroids; Azathioprine; Mycophenolate mofetil
Core Tip	Autoimmune hepatitis (AIH) is a severe liver disease that affects patients worldwide. Conventional treatment with a steroid and azathioprine is the mainstay of treatment. Although elderly patients have a relatively high incidence of AIH, data on its treatment in the elderly are limited. We focused on this subgroup of patients and systematically reviewed studies testing both efficacy and safety of AIH treatments in old patients. Available data support the use of conventional treatment, while the effect of other drugs has only been tested in small case series.
Publish Date	2019-06-14 09:34
Citation	Durazzo M, Lupi G, Scandella M, Ferro A, Gruden G. Autoimmune hepatitis treatment in the elderly: A systematic review. World J Gastroenterol 2019; 25(22): 2809-2818
URL	https://www.wjgnet.com/1007-9327/full/v25/i22/2809.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i22.2809

Full Article (PDF)	WJG-25-2809.pdf
Full Article (Word)	WJG-25-2809.docx
Manuscript File	47389-Review.doc
Answering Reviewers	47389-Answering reviewers.pdf
Audio Core Tip	47389-Audio core tip.wav
Biostatistics Review Certificate	47389-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	47389-Conflict-of-interest statement.pdf
Copyright License Agreement	47389-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	47389-Language certificate.pdf
Supplementary Material	47389-Supplementary material.pdf
Peer-review Report	47389-Peer-review(s).pdf
Scientific Misconduct Check	47389-Scientific misconduct check.pdf
Scientific Editor Work List	47389-Scientific editor work list.pdf