Publication Name	World Journal of Hepatology
Manuscript ID	4745
Country	Türkiye

Received	2013-07-20 09:33
Peer-Review Started	2013-07-22 19:45
First Decision by Editorial Office Director
Return for Revision	2013-07-29 20:49
Revised
Publication Fee Transferred
Second Decision by Editor	2013-10-11 14:58
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-10-12 00:38
Articles in Press
Edit the Manuscript by Language Editor	2013-10-22 14:25
Typeset the Manuscript	2013-11-06 15:23
Publish the Manuscript Online	2013-11-26 22:03

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Autobiography
Article Title	Increased bone mineral density in patients with non-alcoholic steatohepatitis
Manuscript Source	Invited Manuscript
All Author List	Muhsin Kaya, Devran Işık, Remzi Beştaş, Osman Evliyaoğlu, Veysi Akpolat, Hüseyin Büyükbayram and Mehmet Ali Kaplan
Funding Agency and Grant Number
Corresponding Author	Muhsin Kaya, MD, Department of Gastroenterology, Dicle University, School of Medicine, Diyarbakır 21100, Turkey. muhsinkaya20@hotmail.com
Key Words	Non-alcoholic steatohepatitis; Hepatic osteodystrophy; Bone mineral density
Core Tip	Identifying the relationship between non-alcoholic steatohepatitis and bone mineral density (BMD) and its underlying mechanism is important. We found that patients with biopsy-proven non-alcoholic steatohepatitis (NASH) had higher lumbar BMD and serum 25-OH-vitamin-D3 levels compared to healthy controls. We did not find a significant relationship between serum levels of thyroid hormones, sex hormones, parathormone and cytokines, such as tumor necrosis factor-α, interleukin-1 (IL-1), IL-6, insulin-like growth factor-1, IGFBP-3 levels and BMD. An elevated serum 25-OH-vitamin D3 level may be the principle responsible factor in the increased bone mineral density in patients with NASH.
Publish Date	2013-11-26 22:03
Citation	Kaya M, I??k D, Be?ta? R, Evliyao?lu O, Akpolat V, Büyükbayram H, Kaplan MA. Increased bone mineral density in patients with non-alcoholic steatohepatitis. World J Hepatol 2013; 5(11): 627-634
URL	http://www.wjgnet.com/1948-5182/full/v5/i11/627.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i11.627

Full Article (PDF)	WJH-5-627.pdf
Manuscript File	4745-Review.doc
Answering Reviewers	4745-Answering reviewers.pdf
Copyright License Agreement	4745-Copyright assignment.pdf
Peer-review Report	4745-Peer review(s).pdf
Scientific Editor Work List	4745-Scientific editor work list.doc