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Articles Published Processes
7/26/2019 11:08:19 AM | Browse: 804 | Download: 1276
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Received |
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2019-03-20 00:51 |
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Peer-Review Started |
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2019-03-20 09:42 |
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To Make the First Decision |
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2019-04-17 07:33 |
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Return for Revision |
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2019-04-23 01:06 |
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Revised |
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2019-05-20 21:25 |
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Second Decision |
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2019-06-20 06:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-06-27 17:24 |
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Articles in Press |
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2019-06-27 17:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-07-26 05:58 |
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Publish the Manuscript Online |
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2019-07-26 11:08 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Wilson disease developing osteoarthritic pain in severe acute liver failure: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Kido, Shirou Matsumoto, Keishin Sugawara and Kimotoshi Nakamura |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jun Kido, MD, PhD, Assistant Professor, Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan. kidojun@kuh.kumamoto-u.ac.jp |
| Key Words |
Acute liver failure; New Wilson Index; Osteoarthritis; Wilson disease; Case report; |
| Core Tip |
We present an 11-year-old boy with Wilson disease (WD) who developed osteoarthritis symptoms and acute liver failure, with a New Wilson Index Score (NWIS) of 12. His liver cirrhosis improved, leading to almost normal liver function and liver imaging results, one year after receiving combination therapy with Zn and a chelator. Patients with WD with a NWIS > 11 may be able to survive with treatment with Zn and chelators, without liver transplantation, in cases wherein they present with mild hyperbilirubinemia and stage ≤ II hepatic encephalopathy. Symptoms of associated osteoarthritis may also improve with long-term Zn and chelator therapy. |
| Publish Date |
2019-07-26 11:08 |
| Citation |
Kido J, Matsumoto S, Sugawara K, Nakamura K. Wilson disease developing osteoarthritic pain in severe acute liver failure: A case report. World J Hepatol 2019; 11(7): 607-612 |
| URL |
https://www.wjgnet.com/1948-5182/full/v11/i7/607.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v11.i7.607 |
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